Evidence map›Paper›PMID 35473743›Full record

ArticleBMJ open2022

Study protocol for the Shifting Weight using Intermittent Fasting in night shift workers (SWIFt) study: a three-arm randomised controlled trial comparing three weight loss strategies in night shift workers with obesity.

Michelle Rogers, Alison Coates, Catherine E Huggins, Jillian Dorrian, Angela B Clark, Corinne Davis, Gloria Kw Leung, Rochelle Davis, Yan Yin Phoi, Nicole J Kellow and 5 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Fasting: From Physiology to Pathology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Michelle RogersUniSA Justice & Society, University of South Australia, Adelaide, South Australia, Australia.ORCID 0000-0003-0205-2528
Alison CoatesAlliance for Research in Exercise, Nutrition and Activity (ARENA), University of South Australia, Adelaide, South Australia, Australia.
Catherine E HugginsInstitute for Health Transformation, Deakin University, Burwood, Victoria, Australia.ORCID 0000-0003-3929-7756
Jillian DorrianUniSA Justice & Society, University of South Australia, Adelaide, South Australia, Australia.
Angela B ClarkDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.
Corinne DavisDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.
Gloria Kw LeungDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.
Rochelle DavisDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.
Yan Yin PhoiAlliance for Research in Exercise, Nutrition and Activity (ARENA), University of South Australia, Adelaide, South Australia, Australia.
Nicole J KellowDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.
Marina IacovouCentre of Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Crystal L YatesUniSA Justice & Society, University of South Australia, Adelaide, South Australia, Australia.
Siobhan BanksUniSA Justice & Society, University of South Australia, Adelaide, South Australia, Australia.
Tracey L SlettenDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.
Maxine P BonhamDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia maxine.bonham@monash.edu.
Monash University · AUUniversity of South Australia · AUDeakin University · AUHudson Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionShift workers are at an increased risk of developing obesity and type 2 diabetes. Eating and sleeping out of synchronisation with endogenous circadian rhythms causes weight gain, hyperglycaemia and insulin resistance. Interventions that promote weight loss and reduce the metabolic consequences of eating at night are needed for night shift workers. The aim of this study is to examine the effects of three weight loss strategies on weight loss and insulin resistance (HOMA-IR) in night shift workers. METHODS AND ANALYSIS: A multisite 18-month, three-arm randomised controlled trial comparing three weight loss strategies; continuous energy restriction; and two intermittent fasting strategies whereby participants will fast for 2 days per week (5:2); either during the day (5:2D) or during the night shift (5:2N). Participants will be randomised to a weight loss strategy for 24 weeks (weight loss phase) and followed up 12 months later (maintenance phase). The primary outcomes are weight loss and a change in HOMA-IR. Secondary outcomes include changes in glucose, insulin, blood lipids, body composition, waist circumference, physical activity and quality of life. Assessments will be conducted at baseline, 24 weeks (primary endpoint) and 18 months (12-month follow-up). The intervention will be delivered by research dietitians via a combination of face-to-face and telehealth consultations. Mixed-effect models will be used to identify changes in dependent outcomes (weight and HOMA-IR) with predictor variables of outcomes of group, time and group-time interaction, following an intention-to-treat approach. ETHICS AND DISSEMINATION: The study protocol was approved by Monash Health Human Research Ethics Committee (RES 19-0000-462A) and registered with Monash University Human Research Ethics Committee. Ethical approval has also been obtained from the University of South Australia (HREC ID: 202379) and Ambulance Victoria Research Committee (R19-037). Results from this trial will be disseminated via conference presentations, peer-reviewed journals and student theses. TRIAL REGISTRATION NUMBER: Australian New Zealand Clinical Trials Registry (ACTRN-12619001035112).

Indexed as

Diabetes Mellitus, Type 2Insulin ResistanceFastingHumansObesityQuality of LifeRandomized Controlled Trials as TopicVictoriaWeight LossNUTRITION & DIETETICSPUBLIC HEALTHSLEEP MEDICINE

Identifiers

PMID35473743
PMCPMC9045043
OpenAlexW4224983132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.