Evidence map›Paper›PMID 35473730›Full record

ArticleBMJ open2022

Concurrent vision and hearing impairment associated with cognitive dysfunction in a population aged 85+ years: the Ural Very Old Study.

Mukharram M Bikbov, Gyulli M Kazakbaeva, Ellina M Rakhimova, Iuliia A Rusakova, Albina A Fakhretdinova, Azaliia M Tuliakova, Songhomitra Panda-Jonas, Natalia I Bolshakova, Kamilia R Safiullina, Ainur V Gizzatov and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Dual sensory impairment: Global prevalence, future projections, and its association with cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 4 countries.

Mukharram M BikbovUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Gyulli M KazakbaevaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Ellina M RakhimovaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Iuliia A RusakovaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Albina A FakhretdinovaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Azaliia M TuliakovaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Songhomitra Panda-JonasDepartment of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Manheim, Germany.
Natalia I BolshakovaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Kamilia R SafiullinaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Ainur V GizzatovUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Ildar P PonomarevUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Dilya F YakupovaUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Nail E BaymukhametovUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Nikolay A NikitinUfa Eye Research Institute, Ufa, Bashkortostan, Russian Federation.
Jost B JonasDepartment of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Manheim, Germany Jost.Jonas@medma.uni-heidelberg.de.ORCID 0000-0003-2972-5227
Ufa Eye Research Institute · RUHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the prevalence of vision impairment, hearing impairment and dual sensory impairment (DSI) as combination of vision and hearing impairment, in association with cognitive dysfunction in a population aged 85+ years.

methodsThe cross-sectional population-based Ural Very Old Study, conducted in rural and urban Bashkortostan, Russia, between 2017 and 2020, included a detailed ocular and systemic examination with assessment of moderate to severe vision impairment (MSVI)/blindness (best-corrected visual acuity <6/18), moderate to severe hearing loss (MSHL) and cognitive function.

settingA rural and urban area in Bashkortostan, Russia.

participantsOut of 1882 eligible individuals aged 85+ years, 1526 (81.1%) individuals participated. PRIMARY AND SECONDARY OUTCOME MEASURES: Prevalence of vision, hearing and DSI and cognitive dysfunction.

resultsThe study included 731 (47.9%) individuals (mean age 88.1±2.7 years; median 87 years, range 85-98 years) with measurements of MSVI/blindness, MSHL and cognitive function. The prevalence of MSVI/blindness, MSHL, DSI and dementia were 51.8% (95% CI 48.2% to 55.5%), 33.1% (95% CI 29.7% to 36.5%), 20.5% (95% CI 17.8% to 23.5%) and 48.2% (95% CI 44.5% to 51.8%), respectively. Lower cognitive function score was associated with lower visual acuity (p<0.001) and higher hearing loss score (p=0.03), after adjusting for older age (p=0.001), rural region of habitation (p=0.003), lower educational level (p<0.001) and higher depression score (p<0.001). Higher dementia prevalence was associated with higher MSHL prevalence (OR 2.18 95% CI 1.59 to 2.98; p<0.001), higher MSVI/blindness prevalence (OR 2.09, 95% CI 1.55 to 2.81; p<0.001) and higher DSI prevalence (OR 2.80, 95% CI 1.92 to 4.07; p<0.001).

conclusionsIn this very old, multiethnic population from Russia, DSI (prevalence 20.5%), as compared with hearing impairment (OR 2.18) and vision impairment alone (OR 2.09), had a stronger association (OR 2.80) with dementia. The findings show the importance of hearing and vision impairment, in particular their combined occurrence, for dementia prevalence in an old population.

Indexed as

Cognitive DysfunctionDeafnessDementiaHearing LossVision, LowAged, 80 and overBlindnessCross-Sectional StudiesHumansDementiaEpidemiologyOphthalmology

Identifiers

PMID35473730
PMCPMC9045115
OpenAlexW4224991348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.