Evidence map›Paper›PMID 35473521›Full record

ArticleCombinatorial chemistry & high throughput screening2023

Antioxidation Abilities of Sesquiterpenoids from

Weifeng Dai, Dong Wang, Chonglian Chen, Mi Zhang

Abstract read
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In one paragraph

Article in Combinatorial chemistry & high throughput screening, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Weifeng DaiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Dong WangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Chonglian ChenFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Mi ZhangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Kunming University of Science and Technology · CN

Funding

Applied Basic Research Foundation of Yunnan Province 202101AT070133
6 · The paper itself

Abstract

AIMS AND

objectivesIn our previous study, 21 sesquiterpenoids with different skeleton types were isolated from the radix of Curcuma aromatica Salisb., a traditional Chinese medicine used for treating depression and qi and blood stasis. C. aromatica enhanced PC12 cell viability upon damage by H MATERIALS AND

methodsPC12 cells were simultaneously treated with 400 μM H2O2 and sesquiterpenoid compounds or vitamin E (used as a positive control) for 24 h. The activities of GSH-Px, LDH, CAT, and SOD were detected by ELISA kits. The reactive oxygen species (ROS) level in the cells was determined by the fluorescence probe DCFH-DA. [Ca

resultsAll twenty-one sesquiterpenoids from the radix of C. aromatica increased the activities of GSH-Px, CAT, and SOD, and decreased the LDH leakage, and levels of ROS level and [Ca

conclusionsTwenty-one sesquiterpenoids showed different antioxidation abilities as measured by a model of H

Indexed as

AntioxidantsSesquiterpenesAnimalsCurcumaHydrogen PeroxideRatsReactive Oxygen SpeciesSnailsSuperoxide DismutaseAntioxidantsHydrogen PeroxideReactive Oxygen SpeciesSesquiterpenesSuperoxide DismutaseAntioxidationbioactivityCurcuma aromaticaPC12PLS analysissesquiterpenoids

Identifiers

PMID35473521
OpenAlexW4224999456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.