Evidence map›Paper›PMID 35473497›Full record

ArticleBMC cardiovascular disorders2022

Association of physical activity with the incidence of atrial fibrillation in persons > 65 years old: the Atherosclerosis Risk in Communities (ARIC) study.

Grace Fletcher, Aniqa B Alam, Linzi Li, Faye L Norby, Lin Y Chen, Elsayed Z Soliman, Alvaro Alonso

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Grace FletcherDepartment of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, CNR #3051, Atlanta, GA, 30322, USA.
Aniqa B AlamDepartment of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, CNR #3051, Atlanta, GA, 30322, USA.
Linzi LiDepartment of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, CNR #3051, Atlanta, GA, 30322, USA.
Faye L NorbyDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA, USA.
Lin Y ChenCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Elsayed Z SolimanDepartment of Medicine, Section on Cardiovascular Medicine, Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, CNR #3051, Atlanta, GA, 30322, USA. alvaro.alonso@emory.edu.
Emory University · USSinai Health System · USUniversity of Minnesota Medical Center · USWake Forest University · US

Funding

Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
American Heart Association-American Stroke Association 16EIA26410001NHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005INHLBI NIH HHS K24 HL148521
6 · The paper itself

Abstract

aimsTo evaluate the association of physical activity (PA) with atrial fibrillation (AF) incidence in an elderly population.

methodsWe studied 5166 participants of the Atherosclerosis Risk in Communities cohort examined in 2011-2013 free of AF. Self-reported PA was evaluated with a validated questionnaire. Weekly minutes of leisure-time moderate to vigorous physical activity (MVPA) were calculated and categorized using the 2018 Physical Activity Guidelines for Americans (no activity [0 min/week], low [> 0- < 150 min/week], adequate [150- < 300 min/week], high [≥ 300 min/week]). Incident AF through 2019 was ascertained from hospital discharges and death certificates. Cox models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for AF by levels of physical activity adjusting for potential confounders.

resultsThe mean (SD) age for the sample was 75 (5) years (59% female, 22% Black). During a mean (SD) follow-up time of 6.3 (2.0) years, 703 AF events were identified. The association of MVPA with AF incidence showed a U-shaped relationship. Compared to those not engaging in MVPA, individuals with low MVPA had a 23% lower hazard of AF (HR = 0.77; 95% CI 0.61, 0.96), while those with adequate MVPA had a 14% lower hazard (HR 0.86; 95% CI 0.69, 1.06). High levels of MVPA were not associated with AF risk (HR 0.97; 95% CI 0.78, 1.20).

conclusionThis study suggests that being involved in low to moderate levels of MVPA is associated with lower AF risk, with no evidence of increased risk of AF in those with higher levels of MVPA.

Indexed as

AtherosclerosisAtrial FibrillationAgedExerciseFemaleHumansIncidenceMaleRisk FactorsUnited StatesAtrial fibrillationElderlyPhysical activity

Identifiers

PMID35473497
PMCPMC9044801
OpenAlexW4224444143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.