Evidence map›Paper›PMID 35473345›Full record

Trial reportJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2022

Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome: a randomized controlled trial.

M A Tingting, W U Jie, Yang Lijie, Feng Fen, Yang Huilin, Zhang Jinhua, Zhong Yanjin, Ning Qing, Huang Lirong, Lin Youbing and 6 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Integrated 'omics analysis for the gut microbiota response to moxibustion in a rat model of chronic fatigue syndrome.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

M A TingtingCenter of Preventive Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
W U JieCenter of Preventive Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yang LijieCenter of Preventive Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Feng FenCenter of Preventive Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yang HuilinCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Zhang JinhuaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Zhong YanjinCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Ning QingCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Huang LirongCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Lin YoubingCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yan JueDepartment of acupuncture, Center of Preventive Medicine, Affiliated TCM Hospital of Southwest Medical University, Luzhou 646600, China.
Chen GuiquanDepartment of acupuncture, Center of Preventive Medicine, Affiliated TCM Hospital of Southwest Medical University, Luzhou 646600, China.
Hou TianshuCenter of Preventive Medicine, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu 610021, China.
Wang LiCenter of Preventive Medicine, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu 610021, China.
Ren YuanfangCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Tan JingCenter of Chinese Evidence-Based Medicine, Sichuan University West China Hospital, Chengdu 610041, China.
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the efficacy and safety of ginger-indirect moxibustion for chronic fatigue syndrome (CFS).

methodsIn this central randomized, controlled trial, 290 CFS participants were recruited and randomly allocated to group A (ginger-indirect moxibustion plus acupuncture) or group B (acupuncture alone). The study consisted of a treatment period of 8 weeks with a total of 24 treatments (3 sessions per week, every other day), and a follow-up period of 12 weeks. The outcome was measured by Fatigue Severity Scale (FSS), Psychological Health Report (SPHERE), the Self-rating depression scale (SDS) and the Hamilton anxiety scale (HAMA) at baseline, 2, 4, 6, 8, 12 and 20 weeks.

resultsWith the treatment undergoing, the changes of FSS, SPHERE, SDS and HAMA scores in both groups increased gradually, and the effect maintained at the 12th week. Between groups, significantly higher score changes were seen in group A in FSS after 4 weeks treatment (11.94 9.12, 95%: 0.94, 4.7) and in SPHERE after 2 weeks treatment (3.7 2.27, 95%: 0.56, 2.31). But for SDS and HAMA, the improvement did not differ significantly between groups. No severe adverse events were reported.

conclusionGinger-indirect moxibustion is a safe and effective intervention to relieve fatigue and accompanying physical symptoms of CFS.

Indexed as

Acupuncture TherapyFatigue Syndrome, ChronicMoxibustionZingiber officinaleHumansTreatment Outcomefatigue syndrome, chronicginger-indirect moxibustionrandomized controlled trialsafetytreatment outcome

Identifiers

PMID35473345
PMCPMC9924683
OpenAlexW4224991132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.