Evidence map›Paper›PMID 35473336›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2022

Biosynthesis of titanium dioxide nanoparticles using Hypericum perforatum and Origanum vulgare extracts and their main components, hypericin and carvacrol as promising antibacterial agents.

Mojtaba Khaksarian, Mahmoud Bahmani, Morovat Taherikalani, Behnam Ashrafi, Mahmoud Rafieian-Kopaei, Naser Abbasi

Open access · greenAbstract read
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mojtaba KhaksarianDepartment of Physiology and Pharmacology, School of Medicine, Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mahmoud BahmaniBiotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Morovat TaherikalaniDepartment of Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Behnam AshrafiRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mahmoud Rafieian-KopaeiMedical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Naser AbbasiBiotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Lorestan University of Medical Sciences · IRMedical University of Ilam · IRShahrekord University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the anti-bacterial activities of titanium dioxide (TiO) nanoparticles of Origanum (O.) vulgare and Hypericum (H.) perforatum extracts, carvacrol and hypericin against Staphylococcus (S.) aureus.

methodsIn this study, TiOnanoparticles of O. vulgare and H. perforatum extracts, carvacrol and hypericin, were prepared and their antibacterial effects were evaluated against Staphylococcus (S.) aureus. In this study, scanning electron microscope, fourier transform infrared spectrometer, atomic force microscopy, dynamic light scattering and zeta potential were used to investigate the structure of synthesized drugs.

resultsAnti-bacterial activity of synthesized NPs was tested by minimum inhibitory concentration (MIC), minimum bactericidal concentration and disc diffusion method. MICs of TiO-NPs synthesized using O. vulgare, H. perforatum, carvacrol and hypericin and TiO were obtained 250, 62.5, 250, and 250, and 500 μg/mL, respectively. The MBCs for all of these were obtained 1000 μg/mL.

conclusionGreen-synthesized of TiO nanoparticles provides a promising approach to the use of O. vulgare and H. perforatum, carvacrol and hypericin as novel agents and safer antibacterial compounds, especially anti-S. aureus compounds.

Indexed as

Antineoplastic AgentsHypericumNanoparticlesOriganumAnthracenesAnti-Bacterial AgentsBacteriaCymenesHumansPerylenePlant ExtractsPlant OilsStaphylococcus aureusTitaniumAnthracenesAnti-Bacterial AgentsAntineoplastic AgentscarvacrolCymeneshypericinPerylenePlant ExtractsPlant OilsTitaniumtitanium dioxideactive ingredientanti-infective agentsmedicine, traditionalnano-compoundsplant, medicinal

Identifiers

PMID35473336
PMCPMC11393820
OpenAlexW4224993685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.