Evidence map›Paper›PMID 35472844›Full record

ReviewMedical image analysis2022

Recent advances and clinical applications of deep learning in medical image analysis.

Xuxin Chen, Ximin Wang, Ke Zhang, Kar-Ming Fung, Theresa C Thai, Kathleen Moore, Robert S Mannel, Hong Liu, Bin Zheng, Yuchen Qiu

Registry-linked trialAbstract readReview
In one paragraph

Review in Medical image analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06081569 (Multimodal Deep Learning for the Diagnosis and Assessment of Alzheimer's Disease), which is not on this map. Cited by 343 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
343citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06081569 not yet recruitingnot on this mapstarted 2023, after this paper: background citation

Multimodal Deep Learning for the Diagnosis and Assessment of Alzheimer's Disease

TypeobservationalSponsorFirst Hospital of China Medical UniversityRan2023 to 2026Enrolled300ConditionsAlzheimer Disease, Mild Cognitive ImpairmentArmsgait video, speech video, facial expression video
3 · Its place in the literature

Who cites it

343 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  18. Interpretable deep learning model of circulating genomics for quantitative survival prediction in advanced non-small cell lung cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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283 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xuxin ChenSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Ximin WangSchool of Information Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Ke ZhangSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Kar-Ming FungDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Theresa C ThaiDepartment of Radiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kathleen MooreDepartment of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Robert S MannelDepartment of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Hong LiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Bin ZhengSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Yuchen QiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA. Electronic address: qiuyuchen@ou.edu.

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Raid Aljumaily · 2018 to 2026
$27.1M
Use of 3D Quantitative Optical Methods to Optimize Mebendazole Treatment of Ovarian CancerP20GM135009 · NIGMS · UNIVERSITY OF OKLAHOMA · PI Qinggong Tang · 2022 to 2026
$13.6M
NCI NIH HHS P30 CA225520NIGMS NIH HHS P20 GM135009
6 · The paper itself

Abstract

Deep learning has received extensive research interest in developing new medical image processing algorithms, and deep learning based models have been remarkably successful in a variety of medical imaging tasks to support disease detection and diagnosis. Despite the success, the further improvement of deep learning models in medical image analysis is majorly bottlenecked by the lack of large-sized and well-annotated datasets. In the past five years, many studies have focused on addressing this challenge. In this paper, we reviewed and summarized these recent studies to provide a comprehensive overview of applying deep learning methods in various medical image analysis tasks. Especially, we emphasize the latest progress and contributions of state-of-the-art unsupervised and semi-supervised deep learning in medical image analysis, which are summarized based on different application scenarios, including classification, segmentation, detection, and image registration. We also discuss major technical challenges and suggest possible solutions in the future research efforts.

Indexed as

Deep LearningAlgorithmsDiagnostic ImagingHumansImage Processing, Computer-AssistedSupervised Machine LearningAttentionClassificationDeep learningDetectionMedical imagesRegistrationSegmentationSelf-supervised learningSemi-supervised learningUnsupervised learningVision Transformer

Identifiers

PMID35472844
PMCPMC9156578

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.