Evidence map›Paper›PMID 35472147›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2022

Letermovir for Cytomegalovirus Prevention in Adolescent Patients Following Hematopoietic Cell Transplantation.

Nicole P Daukshus, Anthony Cirincione, Molly Siver, Sherry Mathew, Binni Kunvarjee, Amelia Chan, Jaap Jan Boelens, Susan K Seo, Genovefa A Papanicolaou, Nancy A Kernan

Open access · greenAbstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nicole P DaukshusDepartment of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0001-5975-1245
Anthony CirincioneDepartment of Pharmacy, Maine Medical Center, Portland, Maine, USA.
Molly SiverDepartment of Pharmacy, Hackensack University Medical Center, Hackensack, New Jersey, USA.
Sherry MathewDepartment of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Binni KunvarjeeDepartment of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Amelia ChanDepartment of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jaap Jan BoelensStem Cell Transplantation and Cellular Therapies, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Susan K SeoInfectious Disease Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Genovefa A PapanicolaouInfectious Disease Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Nancy A KernanStem Cell Transplantation and Cellular Therapies, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Memorial Sloan Kettering Cancer Center · USHackensack University Medical Center · USMaine Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
National Cancer Institute (NCI) Cancer Center 30 CA008748NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

There are limited data for letermovir as primary cytomegalovirus (CMV) prophylaxis in patients less than 18 years of age. We report 9 adolescent patients who received letermovir following hematopoietic cell transplantation. No patients developed clinically significant CMV while taking letermovir. Letermovir was well tolerated and efficacious in preventing CMV infections.

Indexed as

AcetatesAntiviral AgentsCytomegalovirus InfectionsHematopoietic Stem Cell TransplantationQuinazolinesAdolescentCytomegalovirusHumansAcetatesAntiviral AgentsletermovirQuinazolinesadolescentscytomegalovirushematopoietic cell transplantletermovir

Identifiers

PMID35472147
PMCPMC9989834
OpenAlexW4225002437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.