ArticleBrain : a journal of neurology2022
Reframing postconcussional syndrome as an interface disorder of neurology, psychiatry and psychology.
Article in Brain : a journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk of suicidal behaviors following sport-related and non-sport-related concussion: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Retired contact sports athletes with cognitive concerns: promoting lifelong brain health.Practical neurology · 2026Review
- Prevalence of post-concussion-like symptoms in children and adolescents in Germany: a cross-sectional study.BMC pediatrics · 2026Article
- Transdiagnostic neural correlates of post-traumatic stress disorder and mild traumatic brain injury.Brain communications · 2026Article
- Brain health concerns in former rugby players: clinical and cognitive phenotypes.Brain : a journal of neurology · 2025Article
- Examining and comparing the clinical characteristics of adults with persisting post-concussion symptoms presenting for outpatient rehabilitation following a mild traumatic brain injury or a minimal head injury.Journal of rehabilitation medicine · 2025Article
- The network-based underpinnings of persisting symptoms after concussion: a multimodal neuroimaging meta-analysis.Nature. Mental health · 2025Article
- Structural Magnetic Resonance Imaging Brain Age Investigation in Athletes with Persistent Postconcussion Syndrome.Neurotrauma reports · 2025Article
- Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study.European journal of neurology · 2025Article
- Words Matter: "Functional Neurologic Disorder" or "Functional Symptom Disorder"?Neurology. Clinical practice · 2024Article
- Art therapy and brain injury: making the invisible visible.Frontiers in psychology · 2024Article
- Review on the Role of Salivary Biomarkers in the Diagnosis of Mild Traumatic Brain Injury and Post-Concussion Syndrome.Diagnostics (Basel, Switzerland) · 2023Review
- Management of Psychological Complications Following Mild Traumatic Brain Injury.Current neurology and neuroscience reports · 2023Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Persistent symptoms following a minor head injury can cause significant morbidity, yet the underlying mechanisms for this are poorly understood. The shortcomings of the current terminology that refer to non-specific symptom clusters is discussed. This update considers the need for a multi-dimensional approach for the heterogenous mechanisms driving persistent symptoms after mild traumatic brain injury. Relevant pathophysiology is discussed to make the case for mild traumatic brain injury to be conceptualized as an interface disorder spanning neurology, psychiatry and psychology. The relevance of pre-injury factors, psychological co-morbidities and their interaction with the injury to produce persistent symptoms are reviewed. The interplay with psychiatric diagnoses, functional and somatic symptom disorder presentations and the influence of the medicolegal process is considered. The judicious use and interpretation of investigations given the above complexity is discussed, with suggestions of how the explanation of the diagnostic formulation to the patient can be tailored, including insight into the above processes, to aid recovery. Moving beyond the one-dimensional concept of 'postconcussional syndrome' and reframing the cause of persistent symptoms following mild traumatic brain injury in a bio-psycho-socio-ecological model will hopefully improve understanding of the underlying contributory mechanistic interactions and facilitate treatment.
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Registered trials
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