Evidence map›Paper›PMID 35471849›Full record

Observational studyChronic respiratory disease

Characterisation of the post-tuberculous phenotype of bronchiectasis: A real-world observational study.

Isaac Fong, Teck Boon Low, Anthony Yii

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. A systematic literature review of the clinical and socioeconomic burden of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. The importance of symptoms in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Post-tuberculosis lung disease.Breathe (Sheffield, England) · 2026
    Review
  4. Review
  5. Neutrophilic inflammation in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  6. Article
  7. Incidence and Risk Factors of Tuberculosis-Associated Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025
    Article
  8. Epidemiology of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  9. Long term management of people with post-tuberculosis lung disease.The Korean journal of internal medicine · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Profile of patients with post-tuberculosis bronchiectasis in a tertiary care hospital in Brazil.Journal of clinical tuberculosis and other mycobacterial diseases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Isaac FongDepartment of Respiratory and Critical Care Medicine, 26674Changi General Hospital, Singapore, Singapore.ORCID 0000-0003-3257-2137
Teck Boon LowDepartment of Respiratory and Critical Care Medicine, 26674Changi General Hospital, Singapore, Singapore.
Anthony YiiDepartment of Respiratory and Critical Care Medicine, 26674Changi General Hospital, Singapore, Singapore.
Changi General Hospital · SGRaffles Institution · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBronchiectasis is a heterogeneous disease with distinct phenotypes. The post-tuberculosis (post-TB) bronchiectasis phenotype is prevalent in many countries but is under-studied. Our aim was to identify distinct phenotypic characteristics of post-TB bronchiectasis.

methodsWe recruited adults admitted between Jan 2010-Oct 2017 at Changi General Hospital, Singapore for bronchiectasis exacerbation. We collected demographics, symptoms, lung function, microbiology and FACED scores. Participants were followed-up until the next hospitalized exacerbation or end of study, whichever was sooner. Participants diagnosed by their attending respiratory specialist to have post-TB bronchiectasis were compared to those with bronchiectasis from other aetiologies.

results148 participants were included with mean±standard deviation age 63 ± 9 years; 46 (31.1%) had post-TB bronchiectasis and 102 (68.9%) other aetiologies. Compared to other aetiologies, participants with post-TB bronchiectasis had significantly lower body mass index (BMI), more frequent presentation with haemoptysis, lower forced expiratory volume in one second (FEV

conclusionPost-TB bronchiectasis is a distinct entity with higher rates of haemoptysis and NTM isolation, more frequent exacerbations, and greater disease severity.

Indexed as

BronchiectasisTuberculosisTuberculosis, PulmonaryHemoptysisHumansNontuberculous MycobacteriaPhenotypeBronchiectasisexacerbationpost-tuberculousseverityTuberculosis

Identifiers

PMID35471849
PMCPMC9052827
OpenAlexW4224984579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.