Evidence map›Paper›PMID 35471642›Full record

ArticleObesity (Silver Spring, Md.)2022

Lipid peroxidation biomarkers associated with height and obesity measures in the opposite direction in women.

Mengjie Li, Yingya Zhao, Qi Dai, Ginger Milne, Jirong Long, Qiuyin Cai, Qingxia Chen, Xianglan Zhang, Qing Lan, Nathaniel Rothman and 4 more

Open access · greenAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. Identification of novel FRedox biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Mengjie LiDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Yingya ZhaoDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Qi DaiDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Ginger MilneDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA.
Jirong LongDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Qiuyin CaiDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Qingxia ChenDepartment of Biostatistics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA.
Xianglan ZhangTennessee Department of Health, Nashville, Tennessee, USA.
Qing LanDivision of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA.
Nathaniel RothmanDivision of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA.
Yu-Tang GaoShanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xiao-Ou ShuDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.
Gong YangDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0000-0002-7006-5825
Vanderbilt University Medical Center · USNational Cancer Institute · USRenji Hospital · CNTennessee Department of Health · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
Time-dependent and bidirectional effect of oxidative stress - a missing piece of the free radical theory of cancer and its potential implicationsR01CA237895 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHEN, QINGXIA, YANG, GONG · 2020 to 2025
$3.4M
Inflammatory Biomarkers and Colorectal Cancer RiskR01CA122364 · NCI · VANDERBILT UNIVERSITY · PI YANG, GONG · 2007 to 2010
$1.2M
Oxidative Stress, Antioxidants and Breast Cancer RiskR01CA106591 · NCI · VANDERBILT UNIVERSITY · PI DAI, QI · 2004 to 2007
$973k
NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA106591NCI NIH HHS R01 CA122364NCI NIH HHS R01 CA237895NCI NIH HHS UM1 CA182910
6 · The paper itself

Abstract

objectiveThis study aimed to investigate whether and how lipid peroxidation markers are associated with height and obesity measures.

methodsIn two independent samples of women (Study 1: n = 1,005; Study 2: n = 1,158), systemic levels of lipid peroxidation were assessed by urinary markers F

resultsAfter adjusting for potential confounders, it was found that measured adult height was inversely associated with levels of F

conclusionsThis study, for the first time, to our knowledge, reveals that a shared biological process (lipid peroxidation) is associated with both height and obesity measures but in the opposite direction.

Indexed as

F2-IsoprostanesOxidative StressAdultBiomarkersFemaleHumansLipid PeroxidationObesityBiomarkersF2-Isoprostanes

Identifiers

PMID35471642
PMCPMC9556262
OpenAlexW4224943741

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.