ArticleReproductive sciences (Thousand Oaks, Calif.)2022
Hormonal Influence in Stress Urinary Incontinence During Pregnancy and Postpartum.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Risk Factors for Gestational Stress Urinary Incontinence: Systematic Review and Meta-Analysis.International urogynecology journal · 2026Pooled it
- Urinary incontinence during pregnancy and in the postpartum period.Nature reviews. Urology · 2026Review
- Association between systemic immune-inflammation index and urinary incontinence: Evidence from the National Health and Nutrition Examination Survey.The Journal of international medical research · 2026Article
- Hormonal Contraception Use and Risk of Lower Urinary Tract Symptoms and Conditions: Findings From the Boston Area Community Health Survey.International urogynecology journal · 2026Article
- Effects of exercise during pregnancy on maternal and newborn outcomes.BMC pregnancy and childbirth · 2025Review
- Involuntary Urine Loss in Menopause-A Narrative Review.Journal of clinical medicine · 2025Review
- Association Between History of Gestational Diabetes Mellitus and the Risk of Urinary Leakage in Women: A Cross-Sectional Study.Health science reports · 2025Article
- Construction and Evaluation of a Risk Prediction Model for Stress Urinary Incontinence in Late Pregnancy Based on Clinical Factors and Pelvic Floor Ultrasound Parameters.Diagnostics (Basel, Switzerland) · 2025Article
- Effect of lattice COWorld journal of psychiatry · 2025Article
- Pelvic floor dysfunction in patients with gestational diabetes mellitus.World journal of diabetes · 2025Article
- Relationship between relaxin-2 levels in serum and mode of conception in twin gestations: A prospective cohort study.The journal of obstetrics and gynaecology research · 2025Article
- Effects of postpartum hormonal changes on the immune system and their role in recovery.Acta biochimica Polonica · 2025Review
- A Commentary on "Pelvic Floor Ultrasound Findings and Symptoms of Pelvic Floor Dysfunction During Pregnancy".International urogynecology journal · 2024Article
- Correlation of serum circulating testosterone levels with stress urinary incontinence in postmenopausal women.World journal of urology · 2023Article
- Factors involved in changes in the levator ani during pregnancy.International urogynecology journal · 2023Observational
- Longitudinal Course of Sex Steroids From Pregnancy to Postpartum.Endocrinology · 2023Review
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hormonal changes have been proposed as an etiological factor of stress urinary incontinence (SUI) during pregnancy. Our main objective was to demonstrate the role of hormones in SUI development during pregnancy and postpartum. A prospective longitudinal study was designed. Primiparous women without previous urinary incontinence symptoms were included. Symptoms and Quality of Life (QoL) Questionnaires, physical examinations, and hormone concentration (progesterone, estradiol, and relaxin) were collected twice during pregnancy and three times during postpartum. Logistic regression models, with Wald's forward variable selection method, were used. Prevalence of SUI was 11% in the first trimester, 50% in the third trimester, and 16.4% at 6 months postpartum. The risk of developing SUI throughout pregnancy is higher in women with higher progesterone concentration in the first trimester (OR 1.38, 95% CI 1.06-1.81, p < 0.05) and it is lower in women with stronger pelvic floor muscles in the first trimester (OR 0.35, 95% CI 0.17-0.72, p < 0.05). When occurred during pregnancy, SUI has a 14-fold higher risk of persistence 6 months after birth. In addition, the severity of these symptoms is also an independent risk factor for SUI persistence at 6 months postpartum (OR 1.41, 95% CI 1.15-1.73, p < 0.05). Quality of Life was affected for pregnant women with SUI symptoms. SUI is a highly prevalent condition during pregnancy, affecting the QoL of women in many areas. Higher concentration of progesterone can play a role in SUI development during pregnancy. The presence and severity of SUI during pregnancy are risk factors for the persistence of symptoms 6 months postpartum. Sustaining an optimal pelvic floor muscle strength could prevent SUI during pregnancy.
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Registered trials
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