Evidence map›Paper›PMID 35471095›Full record

ArticleMicrobiology spectrum2022

Diagnostic Performance of Xpert MTB/RIF Ultra Compared with Predecessor Test, Xpert MTB/RIF, in a Low TB Incidence Setting: a Retrospective Service Evaluation.

Mary Mansfield, Anne Marie McLaughlin, Emma Roycroft, Lorraine Montgomery, Joseph Keane, Margaret M Fitzgibbon, Thomas R Rogers

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Diagnostic accuracy of Xpert MTB/RIF Ultra for detecting pulmonary tuberculosis and rifampicin resistance: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Rapid Extensively Drug-Resistant (XDR) TB Diagnosis: An In-House DNA Biochip for Drug Resistance Detection and Mutation Profiling ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  3. Article
  4. Article
  5. Infection and drug resistance · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mary MansfieldDepartment of Clinical Microbiology, Trinity College Dublingrid.8217.c, St James's Hospital Campus, Dublin, Ireland.ORCID 0000-0001-5248-843X
Anne Marie McLaughlinDepartment of Respiratory Medicine, St. James's Hospital, Dublin, Ireland.
Emma RoycroftDepartment of Clinical Microbiology, Trinity College Dublingrid.8217.c, St James's Hospital Campus, Dublin, Ireland.
Lorraine MontgomeryIrish Mycobacteria Reference Laboratory, St. James's Hospital, Dublin, Ireland.
Joseph KeaneDepartment of Respiratory Medicine, St. James's Hospital, Dublin, Ireland.
Margaret M FitzgibbonDepartment of Clinical Microbiology, Trinity College Dublingrid.8217.c, St James's Hospital Campus, Dublin, Ireland.ORCID 0000-0001-8822-214X
Thomas R RogersDepartment of Clinical Microbiology, Trinity College Dublingrid.8217.c, St James's Hospital Campus, Dublin, Ireland.ORCID 0000-0003-4336-7729
Trinity College Dublin · IESt. James's Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the performance of Xpert MTB/RIF Ultra (Ultra) compared with its predecessor, Xpert MTB/RIF (Xpert), in the diagnosis of tuberculosis (TB) in a low TB incidence country. Retrospective analysis was performed on 689 clinical samples received between 2015 and 2018, on which Xpert was performed, and on 715 samples, received between 2018 and 2020, on which Ultra was performed. Samples were pulmonary (

Indexed as

Mycobacterium tuberculosisTuberculosisTuberculosis, PulmonaryHumansIncidenceRetrospective StudiesRifampinSensitivity and SpecificityRifampindiagnostic performanceIrelandMycobacterium tuberculosisPCRTBXpert MTB/RIFXpert MTB/RIF Ultra

Identifiers

PMID35471095
PMCPMC9241712
OpenAlexW4224940465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.