Evidence map›Paper›PMID 35471081›Full record

ArticlemBio2022

Endolysin Regulation in Phage Mu Lysis.

Jake S Chamblee, Jolene Ramsey, Yi Chen, Lori T Maddox, Curtis Ross, Kam H To, Jesse L Cahill, Ry Young

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Phage N4 uses a SAR endolysin-holin system for host cell lysis.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Identifying components of theJournal of bacteriology · 2024
    Article
  10. Article
  11. Microbiology spectrum · 2024
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jake S Chamblee *Center for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-9810-9589
Jolene RamseyCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-3774-5896
Yi ChenCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Lori T MaddoxCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-0096-1269
Curtis RossCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Kam H ToCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Jesse L CahillCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Ry YoungCenter for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-8001-2914
Texas A&M University · US

Funding

CONTROL OF VIRUS-INDUCED LYSISR01GM027099 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI YOUNG, RYLAND FLETCHER · 1985 to 2019
$4.6M
CONTROL OF VIRUS INDUCED LYSISR37GM027099 · NIGMS · TEXAS A&M UNIVERSITY SYSTEM · PI YOUNG, RYLAND F. · 1996 to 2005
$2.4M
Phage LysisR35GM136396 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI YOUNG, RYLAND FLETCHER · 2020 to 2024
$1.9M
NIGMS NIH HHS R01 GM027099NIGMS NIH HHS R35 GM136396NIGMS NIH HHS R37 GM027099
6 · The paper itself

Abstract

Bacteriophage Mu is a paradigm coliphage studied mainly because of its use of transposition for genome replication. However, in extensive nonsense mutant screens, only one lysis gene has been identified, the endolysin gp22. This is surprising because in Gram-negative hosts, lysis by

Indexed as

Bacteriophage muBacteriophagesEndopeptidasesMembrane ProteinsViral ProteinsendolysinEndopeptidasesMembrane ProteinsViral Proteinsbacteriophage lysisbacteriophagesmembranes

Identifiers

PMID35471081
PMCPMC9239132
OpenAlexW4224940443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.