Evidence map›Paper›PMID 35471080›Full record

ArticlemBio2022

Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in

Suresh Kumar, Mehak Zahoor Khan, Neha Khandelwal, Chen Chongtham, Biplab Singha, Ankita Dabla, Debashree Behera, Archana Singh, Balasubramanian Gopal, G Aneeshkumar Arimbasseri and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. mSystems · 2026
    Article
  2. Article
  3. Metabolic Rewiring ofMetabolites · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Suresh KumarNational Institute of Immunology, New Delhi, India.
Mehak Zahoor KhanNational Institute of Immunology, New Delhi, India.
Neha KhandelwalDepartment of Biology, Indian Institute of Science Education and Research, Pune, India.
Chen ChongthamNational Institute of Immunology, New Delhi, India.
Biplab SinghaNational Institute of Immunology, New Delhi, India.
Ankita DablaNational Institute of Immunology, New Delhi, India.
Debashree BeheraMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Archana SinghAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Balasubramanian GopalMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India.ORCID 0000-0001-9097-5052
G Aneeshkumar ArimbasseriNational Institute of Immunology, New Delhi, India.
Siddhesh S KamatDepartment of Biology, Indian Institute of Science Education and Research, Pune, India.
Vinay Kumar NandicooriNational Institute of Immunology, New Delhi, India.ORCID 0000-0002-5682-4178
National Institute of Immunology · INIndian Institute of Science Bangalore · INIndian Institute of Science Education and Research Pune · INAcademy of Scientific and Innovative Research · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

Mycobacterium tuberculosis encodes ~200 transcription factors that modulate gene expression under different microenvironments in the host. Even though high-throughput chromatin immunoprecipitation sequencing and transcriptome sequencing (RNA-seq) studies have identified the regulatory network for ~80% of transcription factors, many transcription factors remain uncharacterized. EmbR is one such transcription factor whose

Indexed as

Bacterial ProteinsMycobacterium tuberculosisTranscription FactorsVirulence FactorsGene Expression Regulation, BacterialHypoxiaBacterial ProteinsTranscription FactorsVirulence FactorsEmbRgranulomahypoxiamycobacteriaMycobacterium tuberculosistranscriptiontranscription factorstuberculosis

Identifiers

PMID35471080
PMCPMC9239209
OpenAlexW4224922590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.