Evidence map›Paper›PMID 35470965›Full record

ArticleUnited European gastroenterology journal2022

Morbid obesity increases death and dropout from the liver transplantation waiting list: A prospective cohort study.

Claire Delacôte, Mathilde Favre, Medhi El Amrani, Massih Ningarhari, Elise Lemaitre, Line Carolle Ntandja-Wandji, Pierre Bauvin, Emmanuel Boleslawski, Guillaume Millet, Stephanie Truant and 8 more

Open access · hybridAbstract read
In one paragraph

Article in United European gastroenterology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Temporal changes in obesity and outcomes for patients listed for liver transplant.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Burden of obesity in gastrointestinal and liver diseases.United European gastroenterology journal · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Claire DelacôteINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Mathilde FavreService des maladies de l'appareil, digestif, University Lille, CHU de Lille, Lille, France.
Medhi El AmraniService de chirurgie digestive et transplantation hépatique, CHRU de Lille, Lille, France.
Massih NingarhariINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Elise LemaitreINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Line Carolle Ntandja-WandjiINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Pierre BauvinINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Emmanuel BoleslawskiService de chirurgie digestive et transplantation hépatique, CHRU de Lille, Lille, France.
Guillaume MilletService de chirurgie digestive et transplantation hépatique, CHRU de Lille, Lille, France.
Stephanie TruantService de chirurgie digestive et transplantation hépatique, CHRU de Lille, Lille, France.
Philippe MathurinINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Alexandre LouvetINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Valérie CanvaService des maladies de l'appareil, digestif, University Lille, CHU de Lille, Lille, France.
Gilles LebuffeService de chirurgie digestive et transplantation hépatique, CHRU de Lille, Lille, France.
François René PruvotService de chirurgie digestive et transplantation hépatique, CHRU de Lille, Lille, France.
Sébastien DharancyINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.
Guillaume LassaillyINSERM U1286, INFINTE, Institute for Translational Research in Inflammation, University Lille, Lille, France.ORCID 0000-0002-6955-244X
French ABM study group
Inserm · FRCentre Hospitalier Universitaire de Lille · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplant (LT) candidates with a body mass index (BMI) over 40 kg/m

methodData between January 2007 and December 2017 were extracted from the French prospective national database: CRISTAL. Competing risk analyses were performed to evaluate predictors of receiving LT. Competitive events were (1) death/WL removal for disease aggravation or (2) improvement. The link between grade obesity, grafts propositions, and reason for refusal was studied.

results15,184 patients were analysed: 10,813 transplant, 2847 death/dropout for aggravation, 748 redirected for improvement, and 776 censored. Mortality/dropout were higher in BMI over 35 (18% vs. 14% 1 year after listing) than in other candidates. In multivariate analysis, BMI>35, age, hepatic encephalopathy, and ascites were independent predictors of death/dropout. Candidates with a BMI ≥ 35 kg/m

conclusionBMI over 35 kg/m

Indexed as

Liver TransplantationObesity, MorbidHumansProspective StudiesRisk AssessmentWaiting Listsaccess to liver graftbody-mass indexdropoutgraft refusalliver transplantationLTmorbid obesitymortalitysevere obesitywaitlist

Identifiers

PMID35470965
PMCPMC9103369
OpenAlexW4224942934

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.