Evidence map›Paper›PMID 35470863›Full record

ReviewActa neurologica Scandinavica2022

Blood biomarkers for HIV infection with focus on neurologic complications-A review.

Lars Hagberg, Arvid Edén, Henrik Zetterberg, Richard W Price, Magnus Gisslén

Open access · hybridAbstract readReview
In one paragraph

Review in Acta neurologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Lars HagbergDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-5685-297X
Arvid EdénDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-2817-9981
Henrik ZetterbergRegion Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-3930-4354
Richard W PriceDepartment of Neurology, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-5429-6044
Magnus GisslénDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-2357-1020
Sahlgrenska University Hospital · SEUniversity of California, San Francisco · US

Funding

European Union Joint Program for Neurodegenerative Disorders JPND2021-00694Knut and Alice Wallenberg Foundation 2020.0241Swedish State Support for Clinical Research #ALFGBG-720931the AD Strategic Fund and the Alzheimer's Association #ADSF-21-831376-Cthe AD Strategic Fund and the Alzheimer's Association #ADSF-21-831377-Cthe AD Strategic Fund and the Alzheimer's Association #ADSF-21-831381-Cthe Alzheimer Drug Discovery Foundation (ADDF), USA #201809-2016862the European Research Council #681712the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant 860197the Olav Thon Foundation, the Erling-Persson Family Foundation, Stiftelsen för Gamla Tjänarinnor, Hjärnfonden, Sweden #FO2019-0228the Swedish Research Council #2018-02532the Swedish Research Council 2021-06545the Swedish state, under an agreement between the Swedish government and the county councils ALFGBG-965885
6 · The paper itself

Abstract

Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA concentrations, CD4 +T-cell count, and neurofilament light chain protein (NfL) concentration, along with tests for opportunistic infections can provide important information for clinical decisions.

Indexed as

HIV InfectionsNervous System DiseasesOpportunistic InfectionsBiomarkersHumansNeurofilament ProteinsBiomarkersNeurofilament Proteinsblood biomarkersHIVneurology

Identifiers

PMID35470863
PMCPMC9324809
OpenAlexW4224938555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.