ArticleJournal of the American Heart Association2022
Association of Accelerometer-Measured Sedentary Accumulation Patterns With Incident Cardiovascular Disease, Cancer, and All-Cause Mortality.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- Associations of accelerometer-based sedentary bouts with adiposity markers among German adults - results from a cross-sectional study.BMC public health · 2023Trial
- Responsiveness of electromyographically assessed skeletal muscle inactivity: methodological exploration and implications for health benefits.Scientific reports · 2022Trial
- Association of wearableZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Device-measured movement behaviours and cancer incidence in a population sample of UK adults: Dual 24-hour analyses of postural and intensity compositions.BMC medicine · 2026Article
- Accelerometry-measured prolonged and interrupted sedentary behavior and cancer incidence and mortality: A cohort study of 91,292 UK Biobank participants.PLoS medicine · 2026Article
- Association of accelerometer-measured physical activity and sedentary behavior with unplanned hospitalization in older adults: a 6-year longitudinal study.GeroScience · 2026Article
- Association of park features with total and prolonged sedentary behavior among older adults: An observational study in Macau.Scientific reports · 2026Observational
- Effectiveness of combined exercise intervention on sedentary behaviour patterns, body composition, and cardiometabolic health among middle-aged adults.BMC sports science, medicine & rehabilitation · 2025Article
- Combined effects of depression and sedentary behavior on mortality risk among older adults: a population-based cohort study.BMC geriatrics · 2025Article
- Sitting time and risk of cancer incidence and cancer mortality in postmenopausal women: the Women's Health Accelerometry Collaboration.Cancer causes & control : CCC · 2025Article
- Reliability and Validity of the Japanese Version of the Exercise Self-Efficacy Scale in Older People Undergoing Lower Extremity Arthroplasty.Nursing & health sciences · 2025Article
- Daily Variability in Sedentary Behaviour and Physical Activity Responsiveness in Older Women.Sensors (Basel, Switzerland) · 2025Article
- Movement behaviors and cardiorespiratory fitness - a cross-sectional compositional data analysis among German adults.BMC sports science, medicine & rehabilitation · 2025Article
- Article
- Physical Activity Fragmentation and Falls in Older Adults: Findings From the National Health and Aging Trends Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Replacing of sedentary behavior with physical activity and the risk of mortality in people with prediabetes and diabetes: a prospective cohort study.The international journal of behavioral nutrition and physical activity · 2023Article
- The association between daily sedentary and active bout frequency with mortality risk in older men using accelerometry.Journal of the American Geriatrics Society · 2023Article
- Association of Accelerometer-Measured Physical Activity and Sedentary Behavior With Incident Cardiovascular Disease, Myocardial Infarction, and Ischemic Stroke: The Women's Health Study.Journal of the American Heart Association · 2023Article
- Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Background Emerging evidence suggests accruing sedentary behavior (SB) in relatively more prolonged periods may convey additional cardiometabolic risks, but few studies have examined prospective outcomes. We examined the association of SB accumulation patterns with incident cardiovascular disease (CVD), cancer, and all-cause mortality (ACM). Methods and Results Data were from 7671 EPIC-Norfolk (European Prospective Investigation Into Cancer and Nutrition-Norfolk) cohort middle- to older-aged adults who wore accelerometers on the right hip for 4 to 7 days. Cox proportional hazards regression modeled associations between 2 measures of SB accumulation and incident CVD, cancer, and ACM. These were usual SB bout duration (the midpoint of each individual's SB accumulation curve, fitted using nonlinear regression) and alpha (hybrid measure of bout frequency and duration, with higher values indicating relatively shorter bouts and fewer long bouts). Models were adjusted for potential confounders, then further for 24-hour time-use compositions. During mean follow-up time of 6.4 years, 339 ACM, 1106 CVD, and 516 cancer events occurred. Elevated rates of incident cancer and ACM were seen with more prolonged SB accumulation (lower alpha, higher usual SB bout duration) but not CVD. For usual SB bout duration and alpha, respectively, the confounder-adjusted hazard ratios per SD of the exposure were 1.12 (95% CI, 1.02-1.23) and 0.88 (95% CI, 0.79-0.98) with incident cancer and 1.16 (95% CI, 1.07-1.26) and 0.80 (95% CI, 0.72-0.89) with ACM (all
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.