ArticleJournal of the American Heart Association2022
Incremental Prognosis by Left Atrial Functional Assessment: The Left Atrial Coupling Index in Patients With Floppy Mitral Valves.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Predictive Value of Preoperative Left Atrial Coupling Indices for Postoperative Atrial Fibrillation After Isolated CABG.Medicina (Kaunas, Lithuania) · 2026Article
- Left Atrial Volumetric/Mechanical Coupling Index Is Ready for Prime Time Across Clinical Scenarios.Journal of the American Heart Association · 2025Article
- Left Atrial Volumetric/Mechanical Coupling Index in Heart Failure With Preserved Ejection Fraction.Journal of the American Heart Association · 2025Observational
- Disproportionate Left Ventricular Enlargement in Mitral Valve Prolapse: Prevalence, Predictors, and Association With Outcomes.Journal of the American Heart Association · 2025Observational
- Normal reference values of left atrioventricular coupling index on two-Dimensional echocardiography.The international journal of cardiovascular imaging · 2025Article
- Relationship Between Left Atrial Coupling Index and Atrial High-Rate Episodes.Pacing and clinical electrophysiology : PACE · 2025Article
- Prognostic Implications of Cardiac Magnetic Resonance Imaging Characteristics in Primary Mitral Regurgitation.JACC. Advances · 2025Article
- Article
- Prognostic Value of Pre-Operative Transthoracic Echocardiography in Patients with Primary Mitral Regurgitation.Reviews in cardiovascular medicine · 2024Review
- Current and Clinically Relevant Echocardiographic Parameters to Analyze Left Atrial Function.Journal of cardiovascular development and disease · 2024Review
- Left Atrial Coupling Index Predicts Heart Failure in Patients with End Stage Renal Disease.Medicina (Kaunas, Lithuania) · 2024Article
- Primary Atriopathy in Mitral Valve Prolapse: Echocardiographic Evidence and Clinical Implications.Circulation. Cardiovascular imaging · 2024Article
- The Left Atrium: Passive Receptacle or Active Contributor to Mitral Regurgitation Severity and Outcome.JACC. Case reports · 2024Article
- Assessment of left atrial function provides incremental value: the left atrial volumetric/mechanical coupling index in patients with chronic kidney disease.Frontiers in cardiovascular medicine · 2024Article
- Watchful surgery in asymptomatic mitral valve prolapse.Frontiers in cardiovascular medicine · 2023Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Emerging data suggest important prognostic value to left atrial (LA) characteristics, but the independent impact of LA function on outcome remains unsubstantiated. Thus, we aimed to define the incremental prognostic value of LA coupling index (LACI), coupling volumetric and mechanical LA characteristics and calculated as the ratio of left atrial volume index to tissue Doppler imaging a', in a large cohort of patients with isolated floppy mitral valve. Methods and Results All consecutive 4792 patients (61±16 years, 48% women) with isolated floppy mitral valve in sinus rhythm diagnosed at Mayo Clinic from 2003 to 2011, comprehensively characterized and with prospectively measured left atrial volume index and tissue Doppler imaging a' in routine practice, were enrolled, and their long-term survival analyzed. Overall, LACI was 5.8±3.7 and was <5 in 2422 versus ≥5 in 2370 patients. LACI was independently higher with older age, more mitral regurgitation (no 3.8±2.3, mild 5.1±3.0, moderate 6.5±3.8, and severe 7.8±4.3), and with diastolic (higher E/e') and systolic (higher end-systolic dimension) left ventricular dysfunction (all
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