Evidence map›Paper›PMID 35470276›Full record

ArticleAnnals of laboratory medicine2022

Overexpression of Prohibitin 2 Protein is Associated with Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia.

Young Eun Lee, Ha Jin Lim, Ju Heon Park, Hye Ran Kim, Min-Gu Kang, Young Kuk Cho, Jong Hee Shin, Myung Geun Shin

Open access · diamondAbstract read
In one paragraph

Article in Annals of laboratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Young Eun LeeBioMedical Sciences Graduate Program (BMSGP), Chonnam National University and Chonnam National University Hwasun Hospital, Hwasun, Korea.ORCID https://orcid.org/0000-0003-2700-3087
Ha Jin LimDepartment of Laboratory Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Korea.ORCID https://orcid.org/0000-0003-2436-5007
Ju Heon ParkDepartment of Laboratory Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Korea.ORCID https://orcid.org/0000-0002-6842-0234
Hye Ran KimCollege of Korean Medicine, Dongshin University, Naju, Korea.ORCID https://orcid.org/0000-0002-0658-3345
Min-Gu KangDepartment of Laboratory Medicine, Gwangyang Sarang General Hospital, Gwangyang, Korea.ORCID https://orcid.org/0000-0003-4946-8512
Young Kuk ChoDepartment of Medical Laboratory Science, Seoyeong University, Gwangju, Korea.ORCID https://orcid.org/0000-0003-1869-6598
Jong Hee ShinDepartment of Laboratory Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Korea.ORCID https://orcid.org/0000-0001-9593-476X
Myung Geun ShinBioMedical Sciences Graduate Program (BMSGP), Chonnam National University and Chonnam National University Hwasun Hospital, Hwasun, Korea.ORCID https://orcid.org/0000-0002-0372-9185
Chonnam National University Hwasun Hospital · KRDongshin University · KRSeoyeong University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytogenetically normal acute myeloid leukemia (CN-AML) accounts for 40%-50% of all AML cases. Despite advances in understanding the molecular pathophysiology of CN-AML, its clinical outcome remains unsatisfactory and unpredictable. To investigate its clinical implication in CN-AML, we measured the expression of prohibitin 2 (PHB2) using immunohistochemical staining (IHCS) of paraffin-embedded bone marrow sections from 134 CN-AML patients. IHCS results were semi-quantitatively scored. Clinical outcome was analyzed in comparison with other prognostic markers, including

Indexed as

Leukemia, Myeloid, AcuteProhibitinsfms-Like Tyrosine Kinase 3HumansMutationPrognosisRNA, Messengerfms-Like Tyrosine Kinase 3PHB2 protein, humanProhibitinsRNA, MessengerAcute myeloid leukemiaPrognosisProhibitin 2

Identifiers

PMID35470276
PMCPMC9057826
OpenAlexW4224932899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.