Evidence map›Paper›PMID 35470227›Full record

ArticleeNeuro

Multimodal, Multiscale Insights into Hippocampal Seizures Enabled by Transparent, Graphene-Based Microelectrode Arrays.

Patrick J Mulcahey, Yuzhang Chen, Nicolette Driscoll, Brendan B Murphy, Olivia O Dickens, A T Charlie Johnson, Flavia Vitale, Hajime Takano

Abstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patrick J MulcaheyDivision of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Yuzhang ChenDepartment of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID https://orcid.org/0000-0002-7377-861X
Nicolette DriscollDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Brendan B MurphyDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Olivia O DickensGraduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA 19104.
A T Charlie JohnsonDepartment of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104.
Flavia VitaleDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Hajime TakanoDivision of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104 takanoh@chop.edu.ORCID https://orcid.org/0000-0003-3033-2412

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ERIC D MARSH, ROBERT Thomas SCHULTZ · 2021 to 2026
$9.2M
Dynamic Contributions of Identified Neurons to High Frequency OscillationsR21NS106434 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI TAKANO, HAJIME · 2018 to 2019
$475k
NICHD NIH HHS P50 HD105354NINDS NIH HHS R21 NS106434
6 · The paper itself

Abstract

Hippocampal seizures are a defining feature of mesial temporal lobe epilepsy (MTLE). Area CA1 of the hippocampus is commonly implicated in the generation of seizures, which may occur because of the activity of endogenous cell populations or of inputs from other regions within the hippocampal formation. Simultaneously observing activity at the cellular and network scales

Indexed as

Epilepsy, Temporal LobeGraphiteAnimalsHippocampusMiceMicroelectrodesSeizuresGraphitecalcium imagingepilepsyhippocampusmicroelectrode

Identifiers

PMID35470227
PMCPMC9087744

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.