Evidence map›Paper›PMID 35469964›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2022

A Klotho-Derived Peptide as a Possible Novel Drug to Prevent Kidney Fibrosis.

Tamara Isakova, Christopher Yanucil, Christian Faul

Open access · bronzeAbstract readEditorialComment
PubMed Publisher
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Effect ofFrontiers in pharmacology · 2022
    Pooled it
  2. Article
  3. Review
  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tamara IsakovaDivision of Nephrology and Hypertension, Department of Medicine and Center for Translational Metabolism and Health, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: tamara.isakova@northwestern.edu.
Christopher YanucilSection of Mineral Metabolism, Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.
Christian FaulSection of Mineral Metabolism, Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.
University of Alabama at Birmingham · USNorthwestern University · US

Funding

Therapeutics Development Core (Core B)P30DK114857 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHNAPER, H WILLIAM · 2018 to 2022
$5.7M
Professional Development Core for Chicago KUH FORWARDU2CDK129917 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARLENE B CHAPMAN, David J Klumpp · 2021 to 2026
$2.9M
Changes in phosphate metabolism cause pathologic cardiac remodeling in chronic kidney disease (CKD)R01HL145528 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI FAUL, CHRISTIAN, WHITE, KENNETH E · 2019 to 2022
$2.4M
Novel Diagnostics and Therapeutic Targets for Calcification in CKDR01DK110087 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ISAKOVA, TAMARA · 2016 to 2020
$2.3M
ACTIVATION OF CARDIAC FGFR4 CAUSES LEFT VENTRICULAR HYPERTROPHYR01HL128714 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FAUL, CHRISTIAN · 2015 to 2019
$1.9M
Hyperphosphatemia Contributes to Systemic Inflammation and Anemia in Chronic Kidney DiseaseR01DK125459 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FAUL, CHRISTIAN · 2020 to 2023
$1.5M
Mentored patient-oriented research of novel mechanisms for cardiovascular disease in patients with chronic kidney diseaseK24HL150235 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ISAKOVA, TAMARA · 2020 to 2024
$582k
NHLBI NIH HHS K24 HL150235NHLBI NIH HHS R01 HL128714NHLBI NIH HHS R01 HL145528NIDDK NIH HHS P30 DK114857NIDDK NIH HHS R01 DK110087NIDDK NIH HHS R01 DK125459NIDDK NIH HHS U2C DK129917
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Kidney DiseasesFibrosisGlucuronidaseHumansKidneyPeptidesGlucuronidasePeptides

Identifiers

PMID35469964
OpenAlexW4224216280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.