Evidence map›Paper›PMID 35469875›Full record

ArticleThe Science of the total environment2022

Use of wastewater surveillance for early detection of Alpha and Epsilon SARS-CoV-2 variants of concern and estimation of overall COVID-19 infection burden.

Van Vo, Richard L Tillett, Katerina Papp, Shirley Shen, Richard Gu, Andrew Gorzalski, Danielle Siao, Rayma Markland, Ching-Lan Chang, Hayley Baker and 8 more

Open access · hybridAbstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Van VoLaboratory of Neurogenetics and Precision Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Richard L TillettNevada Institute of Personalized Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Katerina PappSouthern Nevada Water Authority, P.O. Box 99954, Las Vegas, NV, 89193, USA.
Shirley ShenNevada Institute of Personalized Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Richard GuLaboratory of Neurogenetics and Precision Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Andrew GorzalskiNevada State Public Health Laboratory, Reno, NV 89597, USA.
Danielle SiaoNevada State Public Health Laboratory, Reno, NV 89597, USA.
Rayma MarklandSouthern Nevada Public Health Laboratory of the Southern Nevada Health District, Las Vegas, NV 89106, USA.
Ching-Lan ChangLaboratory of Neurogenetics and Precision Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Hayley BakerLaboratory of Neurogenetics and Precision Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Jingchun ChenNevada Institute of Personalized Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Martin SchillerNevada Institute of Personalized Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Walter Q BetancourtWater & Energy Sustainable Technology (WEST) Center, University of Arizona, 2959 W. Calle Agua Nueva, Tucson, AZ 85745, USA.
Erin ButterySouthern Nevada Public Health Laboratory of the Southern Nevada Health District, Las Vegas, NV 89106, USA.
Mark PandoriNevada State Public Health Laboratory, Reno, NV 89597, USA.
Michael A PickerSouthern Nevada Public Health Laboratory of the Southern Nevada Health District, Las Vegas, NV 89106, USA.
Daniel GerritySouthern Nevada Water Authority, P.O. Box 99954, Las Vegas, NV, 89193, USA. Electronic address: daniel.gerrity@snwa.com.
Edwin C OhLaboratory of Neurogenetics and Precision Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA; Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA; Department of Internal Medicine, UNLV School of Medicine, University of Nevada Las Vegas, Las Vegas, NV 89154, USA. Electronic address: edwin.oh@unlv.edu.
University of Nevada, Las Vegas · USNevada Division of Public and Behavioral Health · USSouthern Nevada Health District · USSouthern Nevada Water Authority · USUniversity of Arizona · US

Funding

Outreach/Diversity/Pipeline ProjectP20GM103440 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Eduardo A Robleto · 2012 to 2026
$58.0M
The Genome Analysis and Sequencing Pipeline (GASP)P20GM121325 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI CHEN, JINGCHUN · 2018 to 2022
$11.5M
Linking Ciliary Biology to the Functional Annotation of Psychiatric DistordersR01MH109706 · NIMH · UNIVERSITY OF NEVADA LAS VEGAS · PI OH, EDWIN C. · 2016 to 2020
$1.9M
NIGMS NIH HHS P20 GM103440NIGMS NIH HHS P20 GM121325NIMH NIH HHS R01 MH109706
6 · The paper itself

Abstract

A decline in diagnostic testing for SARS-CoV-2 is expected to delay the tracking of COVID-19 variants of concern and interest in the United States. We hypothesize that wastewater surveillance programs provide an effective alternative for detecting emerging variants and assessing COVID-19 incidence, particularly when clinical surveillance is limited. Here, we analyzed SARS-CoV-2 RNA in wastewater from eight locations across Southern Nevada between March 2020 and April 2021. Trends in SARS-CoV-2 RNA concentrations (ranging from 4.3 log

Indexed as

COVID-19SARS-CoV-2HumansRNA, ViralSeroepidemiologic StudiesWastewaterWastewater-Based Epidemiological MonitoringRNA, ViralWastewaterCOVID-19MutationSARS-CoV-2VariantVirusWastewater

Identifiers

PMID35469875
PMCPMC9026949
OpenAlexW4224277324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.