Evidence map›Paper›PMID 35469706›Full record

ArticleBrazilian journal of otorhinolaryngology

Effectiveness of galvanic vestibular evoked myogenic potential for evaluation of Meniere's disease.

Ying Cheng, Yuzhong Zhang, Zichen Chen, Weijun Ma, Yanfei Chen, Qing Zhang, Min Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Prognostic value of vestibular-evoked myogenic potentials for disease progression and treatment response in Ménière's disease and endolymphatic hydrops: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ying ChengDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China.
Yuzhong ZhangDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China.
Zichen ChenDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China.
Weijun MaDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China.
Yanfei ChenDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China.
Qing ZhangDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China; Xinhua Hospital of Shanghai Jiao Tong University School of Medicine, China.
Min XuDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, China. Electronic address: ent551205@163.com.
Second Affiliated Hospital of Xi'an Jiaotong University · CNXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAlthough the cause of Meniere's disease (MD) is not fully understood, endolymphatic hydrops is widely believed to be responsible for MD. Previous studies have used Air-Conducted Sound (ACS)-induced Vestibular Evoked Myogenic Potentials (VEMPs) to evaluate otolithic function in patients with MD. However, the use of Galvanic Vestibular Stimulation-VEMPs (GVS-VEMPs) with other vestibular tests in MD has been rare. This study aimed to explore the application of galvanic VEMPs in assessing MD.

methodsNormal individuals and patients with unilateral definite MD were included in this retrospective study. All participants underwent pure tone audiometry. Ocular and cervical VEMPs induced by GVS, and ACS were recorded. The characteristic parameters of VEMPs (n1 latency, p1 latency, amplitude, and AR) were analyzed.

resultsThe provocation rates of GVS-VEMPs did not differ between MD patients and control individuals. Compared with ACS, GVS could evoke potentials with longer latencies. MD patients presented GVS-VEMPs with lower amplitudes and ACS-cVEMP with shorter latencies and had a higher response rate in GVS-oVEMP. However, no differences or correlations were found in the characteristic parameters of GVS-VEMPs among the different stages of MD.

conclusionsGVS is as effective as ACS for inducing VEMP, and GVS-VEMP recording can detect retrolabyrinthine degeneration in MD. Further research is needed to assess the utility of GVS-VEMP in the evaluation of MD severity. LEVEL OF EVIDENCE: Level 4.

Indexed as

Endolymphatic HydropsMeniere DiseaseVestibular Evoked Myogenic PotentialsHumansOtolithic MembraneRetrospective StudiesAir-Conducted SoundCervical vestibular-evoked myogenic potentialGalvanic Vestibular StimulationMeniere’s diseaseOcular vestibular-evoked myogenic potential

Identifiers

PMID35469706
PMCPMC9760987
OpenAlexW4212961233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.