Evidence map›Paper›PMID 35469491›Full record

ReviewVascular2023

A review on the deeper understanding of inflammation and infection of the thoracic aorta.

Kofi Cox, Ritika Dilip Sundaram, Mara Popescu, Kiran Pillai, Muhammed Kermali, Amer Harky

Full text readReview
In one paragraph

Review in Vascular, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Lupus aortitis mimicking an aortic intramural hematoma.Indian journal of thoracic and cardiovascular surgery · 2025
    Article
  5. Article
  6. Multimodal imaging in Ig G4- related aortitis: case report.Archivos peruanos de cardiologia y cirugia cardiovascular
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kofi CoxFaculty of Medicine, RinggoldID:4915St George's Hospital Medical School, University of London, London, UK.
Ritika Dilip SundaramSchool of Medicine, RinggoldID:223860University of Glasgow, Glasgow, UK.
Mara PopescuFaculty of Medicine, RinggoldID:405987King's College London, London, UK.ORCID 0000-0001-6551-6196
Kiran PillaiFaculty of Medicine, RinggoldID:4915St George's Hospital Medical School, University of London, London, UK.ORCID 0000-0003-1523-2819
Muhammed KermaliFaculty of Medicine, RinggoldID:4915St George's Hospital Medical School, University of London, London, UK.
Amer HarkyDepartment of Cardiothoracic Surgery, RinggoldID:156669Liverpool Heart and Chest Hospital, Chester, UK.ORCID 0000-0001-5507-5841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo review the current literature regarding infection and inflammation of the thoracic aorta and to summarise its aetiologies, pathogenesis and clinical presentation. Additionally, the authors sought to compare diagnostic methods and to analyse the different management options.

methodA comprehensive electronic search using PubMed, MEDLINE, Scopus and Google Scholar was conducted to find relevant journal articles with key search terms including: 'aortitis', 'thoracic aortic infection' and 'surgical management of infected thoracic aortic aneurysms'. Prominent publications from 1995 till present (2021) were analysed to achieve a deeper understanding of thoracic aorta infection and inflammation, and the information was then collated to form this review.

resultsThe literature review revealed that infectious causes are more prominent than non-infectious causes, with Gram positive bacteria such as

conclusionA high index of suspicion and a comprehensive history is required to effectively diagnose and manage infection and inflammation of the thoracic aorta. Differentiating between infectious and inflammatory cases is crucial for management planning, as infectious causes typically require antibiotics and surgical intervention. Over the years, the post treatment results have shown significant improvement due to earlier diagnosis, advancement in surgical options and increasingly specific microbial therapy.

Indexed as

Aortic Aneurysm, ThoracicAortitisAnti-Bacterial AgentsAorta, ThoracicHumansInflammationAnti-Bacterial AgentsAortic aneurysmInfectionMicrobiology

Identifiers

PMID35469491
PMCPMC10021126

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read51
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.