ArticleMaterials today. Bio2022
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Preparation and Characterization of Double-Network Composite Hydrogels with Carboxymethyl Pachymaran in Promoting Wound Healing.Foods (Basel, Switzerland) · 2026Article
- Interpretable Machine Learning Insights into Adhesion and Modulus of Biomedical HA-Dopamine Hydrogels.Gels (Basel, Switzerland) · 2026Article
- Mechanistic Investigation of Microdroplet Formation in High-Viscosity Shear-Thinning Hydrogel Bioinks.Gels (Basel, Switzerland) · 2026Article
- Multifunctional hydrogels for synergistic therapy of cutaneous melanoma-associated tumor recurrence and wound regeneration.Materials today. Bio · 2025Review
- Fabrication of Piezo1 protein encapsulated pressure-sensitive multifunctional hydrogel in modulating cellular response and wound healing in pressure ulcer conditions.Regenerative therapy · 2025Article
- Zinc oxide nanoparticles for skin wound healing: A systematic review from the perspective of disease types.Materials today. Bio · 2025Review
- Biofunctional Carboxymethyl Chitosan Hydrogel Incorporating Hyaluronic Acid and RGD Peptides for Accelerated Wound Repair.Gels (Basel, Switzerland) · 2025Article
- Stimulus-responsive cellulose hydrogels in biomedical applications and challenges.Materials today. Bio · 2025Review
- Development and Characterization of Hyaluronic Acid Graft-Modified Polydopamine Nanoparticles for Antibacterial Studies.Polymers · 2025Article
- Microgels for Cell Delivery in Tissue Engineering and Regenerative Medicine.Nano-micro letters · 2024Review
- Natural blackcurrant extract contained gelatin hydrogel with photothermal and antioxidant properties for infected burn wound healing.Materials today. Bio · 2024Article
- Injectable Hydrogels Based on Hyaluronic Acid and Gelatin Combined with Salvianolic Acid B and Vascular Endothelial Growth Factor for Treatment of Traumatic Brain Injury in Mice.Molecules (Basel, Switzerland) · 2024Article
- Dual green hemostatic sponges constructed by collagen fibers disintegrated fromMaterials today. Bio · 2024Article
- Plant molecules reinforce bone repair: Novel insights into phenol-modified bone tissue engineering scaffolds for the treatment of bone defects.Materials today. Bio · 2024Review
- Fabrication and characteristics of multifunctional hydrogel dressings using dopamine modified hyaluronic acid and phenylboronic acid modified chitosan.Frontiers in chemistry · 2024Article
- Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications.Gels (Basel, Switzerland) · 2023Review
- The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration.European journal of histochemistry : EJH · 2023Review
- Organogel of Acai Oil in Cosmetics: Microstructure, Stability, Rheology and Mechanical Properties.Gels (Basel, Switzerland) · 2023Article
- Cu(II)@MXene based photothermal hydrogel with antioxidative and antibacterial properties for the infected wounds.Frontiers in bioengineering and biotechnology · 2023Article
- Extrusion of Cell Encapsulated in Boron Nitride Nanotubes Reinforced Gelatin-Alginate Bioink for 3D Bioprinting.Gels (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Injectable Hydrogels with adhesive, antioxidant and hemostatic properties are highly desired for promoting skin injury repair. In this study, we prepared a multi-functional carboxymethyl chitosan/hyaluronic acid-dopamine (CMC/HA-DA) hydrogel, which can be crosslinked by horseradish peroxidase and hydrogen peroxide. The antioxidation, gelation time, degradability, rheology and antihemorrhagic properties of hydrogels can be finely tuned by varying composition ratio. The cytocompatibility test and hemolysis test confirmed that the designed hydrogel holds good biocompatibility. More importantly, the repair effect of the hydrogel on full-thickness skin injury model in mice was studied. The results of wound healing, collagen deposition, immunohistochemistry and immunofluorescence showed that CMC/HA-DA hydrogel could significantly promote angiogenesis and cell proliferation at the injured site. Notably, the inflammatory response can also be regulated to promote the repair of full-thickness skin defect in mice. Results indicate that this injectable CMC/HA-DA hydrogel holds high application prospect for promising wound healing.
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