Evidence map›Paper›PMID 35468944›Full record

ArticleCellular & molecular immunology2022

IFN-γ

Lili Chen, Zhengxiang He, Bernardo S Reis, Jesse D Gelles, Jerry Edward Chipuk, Adrian T Ting, Julie A Spicer, Joseph A Trapani, Glaucia C Furtado, Sergio A Lira

Open access · hybridAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Impacts of non-nutritive sweeteners on the human microbiome.Immunometabolism (Cobham, Surrey) · 2025
    Review
  8. DAMP-ing IBD: Extinguish the Fire and Prevent Smoldering.Digestive diseases and sciences · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Lesional senescent CD4Frontiers in immunology · 2024
    Article
  14. Article
  15. Hyper α2,6-Sialylation Promotes CD4Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Lili Chen *Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Zhengxiang He *Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. zhengxiang.he@mssm.edu.ORCID http://orcid.org/0000-0002-8961-859X
Bernardo S ReisLaboratory of Mucosal Immunology, The Rockefeller University, New York, NY, 10065, USA.
Jesse D GellesDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0002-3960-1853
Jerry Edward ChipukDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0002-1337-842X
Adrian T TingDepartment of Immunology, Mayo Clinic, Rochester, MN, 55905, USA.ORCID http://orcid.org/0000-0003-0653-9923
Julie A SpicerAuckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Joseph A TrapaniCancer Immunology Program, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC, 3000, Australia.
Glaucia C FurtadoPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Sergio A LiraPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. sergio.lira@mssm.edu.ORCID http://orcid.org/0000-0002-6742-3089
Icahn School of Medicine at Mount Sinai · USMayo Clinic · USPeter MacCallum Cancer Centre · AURockefeller University · USUniversity of Auckland · NZ

Funding

Mechanisms associated with flares and remission in colitisR01DK110352 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LIRA, SERGIO A. · 2017 to 2025
$5.1M
Chronic Mitochondrial Division and Melanoma: Mechanism, Prognosis, and TherapyR01CA267696 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Jerry Edward Chipuk · 2022 to 2026
$2.4M
Mechanisms associated with diet-induced colitisR01DK121009 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LIRA, SERGIO A. · 2020 to 2023
$2.4M
Function and Regulation of the BCL-2 FamilyR01CA237264 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHIPUK, JERRY EDWARD · 2020 to 2024
$1.9M
NCI NIH HHS R01 CA237264NCI NIH HHS R01 CA267696NIDDK NIH HHS R01 DK110352NIDDK NIH HHS R01 DK121009
6 · The paper itself

Abstract

The food colorant Red 40 is an environmental risk factor for colitis development in mice with increased expression of interleukin (IL)-23. This immune response is mediated by CD4

Indexed as

CD4-Positive T-LymphocytesColitisFood Coloring AgentsInterleukin-23AnimalsInterferon-gammaMiceMice, Inbred C57BLFood Coloring AgentsInterferon-gammaInterleukin-23Allura Red; IL23; Cytotoxic CD4+ T cells; CD4+ CTL; Inflammation; Epithelium damage; Colitis

Identifiers

PMID35468944
PMCPMC9243055
OpenAlexW4224945264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.