Evidence map›Paper›PMID 35468771›Full record

ArticleBMC neurology2022

Involuntary crying episodes with Susac's syndrome-a rare presentation of a rare disease: a case report.

O Alshaqi, T Moodie, A Alchaki

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. The neurocognitive and neuropsychiatric manifestations of Susac syndrome: a brief review of the literature and future directions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

O AlshaqiDamascus University, Damascus, Syria.
T MoodieUniversity of South Dakota, Vermillion, USA.
A AlchakiUniversity of South Dakota, Vermillion, USA. aalchaki@gmail.com.ORCID http://orcid.org/0000-0002-4129-2455
University of South Dakota · USDamascus University · SY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this case, we reported the pseudobulbar affect (PBA) in a patient with Susac's syndrome-a rare condition that was caused by a rare syndrome. Previous case reports of Susac syndrome described psychiatric symptoms such as emotional disturbances or personality changes. Only a few case reports have reported psychiatric disorders in patients with Susac's syndrome. There were no reported cases of Susac syndrome with PBA as an initial presentation. CASE PRESENTATION: Our patient was 56 years old and presented with involuntary crying, left-sided headache, left-sided hearing loss, and tinnitus. Brain MRI showed numerous areas of restricted diffusion and enhancement involving the corpus callosum, bilateral hemispheres, and brainstem. Ophthalmological evaluation showed bilateral branch retinal artery occlusion. She was diagnosed with Susac's syndrome and PBA. She was treated with cyclophosphamide and dextromethorphan hydrobromide/quinidine sulfate with excellent recovery. This is a 2-year clinical course. DISCUSSION AND

conclusionsRecognition of the clinical presentation of Susac's syndrome and PBA with early diagnosis and treatment are the keys to preventing further disability and impact on patients and their families.

Indexed as

Retinal Artery OcclusionSusac SyndromeCorpus CallosumCryingFemaleHumansMiddle AgedRare DiseasesCompulsive laughing or cryingEmotional dysregulationEmotional incontinenceHearing lossInvoluntary cryingPathologic weeping or crying or laughingPseudobulbar effectPseudobulbar laughing or cryingRetinal artery occlusionSusac’s syndrome

Identifiers

PMID35468771
PMCPMC9036746
OpenAlexW4224544495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.