Evidence map›Paper›PMID 35468738›Full record

ReviewBMC infectious diseases2022

Paraplegia secondary to disseminated mucormycosis: case report and literature review.

Xiangjun Shi, Lei Qi, Boran Du, Xingchen Yao, Xinru Du

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Spinal infection caused byFrontiers in medicine · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xiangjun ShiDepartment of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Lei QiDepartment of Orthopaedics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Boran DuDepartment of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Xingchen YaoDepartment of Orthopaedics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Xinru DuDepartment of Orthopaedics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. duxinru@ccmu.edu.cn.
Beijing Chao-Yang Hospital · CNCapital Medical University · CNBeijing Obstetrics and Gynecology Hospital · CN

Funding

Natural Science Foundation of Beijing Municipality 7192071
6 · The paper itself

Abstract

backgroundWe report a case of spine infection with mucormycosis that manifested signs of paraplegia in a patient suffering from disseminated mucormycosis. Timely and effective surgery was performed. A review of the literature is included. CASE PRESENTATION: A patient with diabetic ketoacidosis complained of back pain and fatigue for one month, and his right lower extremity activity had been limited for 10 days. T4-T6 vertebral and paravertebral soft tissue-involved infections were identified by MRI, which were derived from right lung pneumonia. He underwent abscess debridement, spinal canal decompression, pedicle screw fixation and amphotericin B liposome injection. Histopathological examination revealed broad aseptate hyphae suggestive of invasive mucormycosis. There was improvement in neurological function after surgical and medical treatment. Three months after the surgery, the patient died of uncontrollable massive bleeding of the urinary system. Mucormycosis is characterized by rapid development and a high mortality rate. This case shows the significance of a multidisciplinary team in the diagnosis and treatment of patients with mucormycosis. In addition, orthopedic surgeons should design appropriate surgery plans for spine-involved mucormycosis patients.

conclusionThis case present a patient with paraplegia caused by the spread of pulmonary mucormycosis to the vertebral and paravertebral soft tissue of levels T4-T6. After medical treatment, surgical debridement and internal fixation, the patient recovered well but later patient died of possible disease dissemination to the renal or urinary tract which resulted in massive haemorrhage.

Indexed as

MucormycosisAntifungal AgentsHumansMagnetic Resonance ImagingMaleParaplegiaAntifungal AgentsCase reportDisseminated mucormycosisParaplegiaSpine involvedSurgical treatment

Identifiers

PMID35468738
PMCPMC9036692
OpenAlexW4224526100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.