Evidence map›Paper›PMID 35468061›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2022

Manipulation and Mechanical Deformation of Leukemia Cells by High-Frequency Ultrasound Single Beam.

Yushun Zeng, Jia Hao, Junhang Zhang, Laiming Jiang, Sangyeon Youn, Gengxi Lu, Dongliang Yan, Haochen Kang, Yizhe Sun, K Kirk Shung and 2 more

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Pressure estimation of ultra-high frequency ultrasound using gas vesicles.The Journal of the Acoustical Society of America · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yushun Zeng
Jia Hao
Junhang Zhang
Laiming Jiang
Sangyeon Youn
Gengxi Lu
Dongliang Yan
Haochen Kang
Yizhe Sun
K Kirk Shung
Keyue Shen
Qifa Zhou
University of Southern California · US

Funding

Phase resolved ARF optical coherence elastography for intravascular imagingR01HL125084 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ZHOU, QIFA · 2014 to 2023
$5.6M
High-resolution High-speed Photoacoustic and Ultrasound Imaging of SmallVessel Functions in Ischemic StrokeR01NS111039 · NINDS · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2023
$2.7M
(PQ5) Microenvironmental Regulation of Mitochondrial Heterogeneity in Cancer MetastasisR01CA220012 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHEN, KEYUE · 2019 to 2023
$2.2M
Artificial Stromal Cell for Hematopoietic Stem Cell ExpansionR21EB024748 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHEN, KEYUE · 2017 to 2019
$637k
NCI NIH HHS R01 CA220012NHLBI NIH HHS R01 HL125084NIBIB NIH HHS R21 EB024748NINDS NIH HHS R01 NS111039
6 · The paper itself

Abstract

Ultrasound single-beam acoustic tweezer system has attracted increasing attention in the field of biomechanics. Cell biomechanics play a pivotal role in leukemia cell functions. To better understand and compare the cell mechanics of the leukemia cells, herein, we fabricated an acoustic tweezer system in-house connected with a 50-MHz high-frequency cylinder ultrasound transducer. Selected leukemia cells (Jurkat, K562, and MV-411 cells) were cultured, trapped, and manipulated by high-frequency ultrasound single beam, which was transmitted from the ultrasound transducer without contacting any cells. The relative deformability of each leukemia cell was measured, characterized, and compared, and the leukemia cell (Jurkat cell) gaining the highest deformability was highlighted. Our results demonstrate that the high-frequency ultrasound single beam can be utilized to manipulate and characterize leukemia cells, which can be applied to study potential mechanisms in the immune system and cell biomechanics in other cell types.

Indexed as

AcousticsLeukemiaHumansUltrasonography

Identifiers

PMID35468061
PMCPMC9753557
OpenAlexW4224937974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.