ArticleProceedings of the National Academy of Sciences of the United States of America2022
Species divergence in gut-restricted bacteria of social bees.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Colibactin produced by a honeybee gut symbiont mediates pathogen defence.Nature microbiology · 2026Article
- Article
- Microbial Succession on Honey Bee Body Surfaces Reflects Behavioral Maturation.Microorganisms · 2026Article
- Priority effects drive strain-level community composition of honeybee gut microbiota.The ISME journal · 2026Article
- Host and microbial factors influence bacterial colonization of the honey bee gut.The ISME journal · 2026Article
- Gut microbiota of Brazilian Melipona stingless bees: Dominant members and their localization in different gut regions.PloS one · 2026Article
- Colibactin produced by a honeybee symbiont defends against pathogens and shapes the gut community.bioRxiv : the preprint server for biology · 2025Article
- Article
- Evolution of gut microbiota across honeybee species revealed by comparative metagenomics.Nature communications · 2025Article
- Host-Driven Functional Divergence in Gut Microbiota of Honeybees Apis cerana and Apis mellifera: Implications for Pollination, Nutrition, and Sustainable Apiculture.Current microbiology · 2025Article
- Effects of priority on strain-level composition of the honey bee gut community.Applied and environmental microbiology · 2025Article
- Antibiotic treatment of honey bee colonies alters early gut microbiome assembly and induces persistent dysbiosis in newly emerged workers.Scientific reports · 2025Article
- Host specificity of gut microbiota associated with social bees: patterns and processes.Microbiology and molecular biology reviews : MMBR · 2025Review
- Gut microbiota of BrazilianbioRxiv : the preprint server for biology · 2025Article
- Host Specificity ofInsects · 2025Article
- Genomic divergence across the tree of life.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Co-evolution and Gene Transfers Drive Speciation Patterns in Host-Associated Bacteria.Molecular biology and evolution · 2024Article
- Article
- Type VI secretion systems promote intraspecific competition and host interactions in a bee gut symbiont.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Host-associated microbiomes, particularly gut microbiomes, often harbor related but distinct microbial lineages, but how this diversity arises and is maintained is not well understood. A prerequisite for lineage diversification is reproductive isolation imposed by barriers to gene flow. In host-associated microbes, genetic recombination can be disrupted by confinement to different hosts, for example following host speciation, or by niche partitioning within the same host. Taking advantage of the simple gut microbiome of social bees, we explore the diversification of two groups of gut-associated bacteria, Gilliamella and Snodgrassella, which have evolved for 80 million y with honey bees and bumble bees. Our analyses of sequenced genomes show that these lineages have diversified into discrete populations with limited gene flow. Divergence has occurred between symbionts of different host species and, in some cases, between symbiont lineages within a single host individual. Populations have acquired genes to adapt to specific hosts and ecological niches; for example, Gilliamella lineages differ markedly in abilities to degrade dietary polysaccharides and to use the resulting sugar components. Using engineered fluorescent bacteria in vivo, we show that Gilliamella lineages localize to different hindgut regions, corresponding to differences in their abilities to use spatially concentrated nitrogenous wastes of hosts. Our findings show that bee gut bacteria can diversify due to isolation in different host species and also due to spatial niche partitioning within individual hosts, leading to barriers to gene flow.
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