Evidence map›Paper›PMID 35467532›Full record

ArticleeLife2022

Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors.

Soo Jeong Kim, Youngsik Woo, Hyun Jin Kim, Bon Seong Goo, Truong Thi My Nhung, Seol-Ae Lee, Bo Kyoung Suh, Dong Jin Mun, Joung-Hun Kim, Sang Ki Park

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Soo Jeong KimDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0002-6640-9445
Youngsik WooDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0002-8308-8532
Hyun Jin KimDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0001-9108-151X
Bon Seong GooDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.
Truong Thi My NhungDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.
Seol-Ae LeeDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.
Bo Kyoung SuhDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0001-8079-9446
Dong Jin MunDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.
Joung-Hun KimDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.
Sang Ki ParkDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0003-1023-7864
Pohang University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic spines are the central postsynaptic machinery that determines synaptic function. The F-actin within dendritic spines regulates their dynamic formation and elimination. Rai14 is an F-actin-regulating protein with a membrane-shaping function. Here, we identified the roles of Rai14 for the regulation of dendritic spine dynamics associated with stress-induced depressive-like behaviors. Rai14-deficient neurons exhibit reduced dendritic spine density in the

Indexed as

ActinsDendritic SpinesActin CytoskeletonAnimalsDisease Models, AnimalMiceNeuronsTretinoinActinsTretinoincell biologydendritic spine dynamicsdepressive-like behaviormouseneuroscienceRai14tara

Identifiers

PMID35467532
PMCPMC9068211
OpenAlexW4224441459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.