Evidence map›Paper›PMID 35467408›Full record

ArticleMicrobiology spectrum2022

Comparison of Two Distinct Subpopulations of Klebsiella pneumoniae ST16 Co-Occurring in a Single Patient.

Biying Zhang, Renjing Hu, Qinghua Liang, Shuang Liang, Qin Li, Jiawei Bai, Manlin Ding, Feiyang Zhang, Yingshun Zhou

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  4. Plasmid genomic epidemiology ofMicrobial genomics · 2025
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  8. Co-occurrence of ST412mSystems · 2024
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  10. Potential of an Isolated Bacteriophage to InactivateAntibiotics (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Coexistence ofFrontiers in cellular and infection microbiology · 2023
    Article
  13. A Comprehensive Genomic Analysis of the EmergentPathogens (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Biying Zhang *Department of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Renjing Hu *Department of Laboratory Medicine, The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.ORCID 0000-0001-6631-1643
Qinghua LiangDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Shuang LiangDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Qin LiDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Jiawei BaiDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Manlin DingDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Feiyang ZhangDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Yingshun ZhouDepartment of Pathogenic Biology, School of Basic Medicine, Southwest Medical University, Luzhou, Sichuan, China.ORCID 0000-0003-4978-0098
Southwest Medical University · CNWuxi No.2 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The higher resistance rate to ceftazidime-avibactam (CZA) is mainly related to carbapenem resistance, especially New Delhi metallo-β-lactamase (NDM). The CZA-susceptible Klebsiella pneumoniae (K191663) and the later CZA-resistant isolates (K191724, K191725, K191773) co-producing NDM-4 and OXA-181 were obtained from the same hospitalized patient returning from Vietnam. Our study aims to elucidate the diversity of K. pneumoniae ST16 through comparative analysis of whole-genome sequencing (WGS) data and identify the potential evolution of plasmids by sequencing longitudinal clinical isolates during antibiotic treatment. Firstly, multilocus sequence typing analysis and phylogenic analysis suggested that these strains belong to the two lineages of K. pneumoniae ST16. Surprisingly, the CZA-resistant strains were closely related to K. pneumoniae ST16 described in South Korea, instead of the

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsEscherichia coliHumansInterleukin-24InterleukinsMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsInterleukin-24Interleukinscarbapenemase-producing Klebsiella pneumoniaeceftazidime–avibactamIS26NDM-4OXA-181ST16whole-genome sequencing

Identifiers

PMID35467408
PMCPMC9241866
OpenAlexW4224435190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.