Evidence map›Paper›PMID 35467395›Full record

ArticleMicrobiology spectrum2022

Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids against Staphylococcus aureus.

Aaron B Benjamin, Madeleine G Moule, Maruti K Didwania, Jonathan Hardy, Panatda Saenkham-Huntsinger, Preeti Sule, Josefine Eilsø Nielsen, Jennifer S Lin, Christopher H Contag, Annelise E Barron and 1 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Antibiotic Resistance ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based onInternational journal of molecular sciences · 2024
    Review
  8. Review
  9. Article
  10. Antibiofilm properties of cathelicidin LL-37: an in-depth review.World journal of microbiology & biotechnology · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aaron B Benjamin *Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, College Station, Texas, USA.ORCID 0000-0003-4387-2434
Madeleine G Moule *Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, College Station, Texas, USA.
Maruti K DidwaniaDepartment of Bioengineering, Stanford Universitygrid.168010.egrid.471392.agrid.168010.e School of Medicine and of Engineering, Stanford, California, USA.
Jonathan HardyInstitute for Quantitative Health Science and Engineering, Departments of Biomedical Engineering and Microbiology & Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
Panatda Saenkham-HuntsingerDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, College Station, Texas, USA.
Preeti SuleDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, College Station, Texas, USA.
Josefine Eilsø NielsenDepartment of Bioengineering, Stanford Universitygrid.168010.egrid.471392.agrid.168010.e School of Medicine and of Engineering, Stanford, California, USA.
Jennifer S LinDepartment of Bioengineering, Stanford Universitygrid.168010.egrid.471392.agrid.168010.e School of Medicine and of Engineering, Stanford, California, USA.
Christopher H ContagInstitute for Quantitative Health Science and Engineering, Departments of Biomedical Engineering and Microbiology & Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0002-1011-8278
Annelise E BarronDepartment of Bioengineering, Stanford Universitygrid.168010.egrid.471392.agrid.168010.e School of Medicine and of Engineering, Stanford, California, USA.
Jeffrey D CirilloDepartment of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, College Station, Texas, USA.ORCID 0000-0003-3058-2702

Funding

Role of Innate Immune Dysregulation in the Etiology of DementiaDP1AG072438 · NIA · STANFORD UNIVERSITY · PI BARRON, ANNELISE EMILY · 2020 to 2024
$5.2M
Application of Imaging to Development of Tuberculosis InterventionsR01AI104960 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI CIRILLO, JEFFREY D. · 2014 to 2018
$1.9M
Ampetoids as Biostable Functional Mimics of Antimicrobial PeptidesR01AI072666 · NIAID · STANFORD UNIVERSITY · PI BARRON, ANNELISE EMILY · 2007 to 2011
$1.8M
Design of hetero-multivalent targeted liposome for combating intracellular Mycobacterium tuberculosisR21AI149383 · NIAID · TEXAS ENGINEERING EXPERIMENT STATION · PI CIRILLO, JEFFREY D., WU, HUNG-JEN · 2020 to 2021
$416k
NIAID NIH HHS R01 AI072666NIAID NIH HHS R01 AI104960NIAID NIH HHS R21 AI149383NIA NIH HHS DP1 AG072438
6 · The paper itself

Abstract

Staphylococcus aureus is one of the most common pathogens associated with infection in wounds. The current standard of care uses a combination of disinfection and drainage followed by conventional antibiotics such as methicillin. Methicillin and vancomycin resistance has rendered these treatments ineffective, often causing the reemergence of infection. This study examines the use of antimicrobial peptoids (sequence-specific poly-

Indexed as

Anti-Infective AgentsMethicillin-Resistant Staphylococcus aureusPeptoidsStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesBiofilmsCathelicidinsMethicillinMiceMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial Cationic PeptidesCathelicidinsMethicillinPeptoidsantimicrobial peptideschemical synthesisStaphylococcus aureus

Identifiers

PMID35467395
PMCPMC9241801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.