Evidence map›Paper›PMID 35467389›Full record

ArticleMicrobiology spectrum2022

Whole-Genome Shotgun Metagenomic Sequencing Reveals Distinct Gut Microbiome Signatures of Obese Cats.

Xiaolei Ma, Emily Brinker, Emily C Graff, Wenqi Cao, Amanda L Gross, Aime K Johnson, Chao Zhang, Douglas R Martin, Xu Wang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Worldwide research trends on theFrontiers in immunology · 2026
    Pooled it
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  9. Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Xiaolei MaDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Emily BrinkerDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Emily C GraffDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Wenqi CaoDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Amanda L GrossScott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Aime K JohnsonDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Chao ZhangDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Institute of Precision Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Douglas R MartinScott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.
Xu WangDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.ORCID 0000-0002-7594-5004
Auburn University · USArkansas Agricultural Experiment Station · USShanghai Jiao Tong University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overweight and obesity are growing health problems in domestic cats, increasing the risks of insulin resistance, lipid dyscrasias, neoplasia, cardiovascular disease, and decreasing longevity. The signature of obesity in the feline gut microbiota has not been studied at the whole-genome metagenomic level. We performed whole-genome shotgun metagenomic sequencing in the fecal samples of eight overweight/obese and eight normal cats housed in the same research environment. We obtained 271 Gbp of sequences and generated a 961-Mbp

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaCatsFecesMetagenomeMiceObesityOverweightWeight LossBifidobacteriumCampylobacterDialisterErysipelotrichaceaefeline obesityFirmicutes-to-Bacteroidetes ratiogut microbiotaOlsenella

Identifiers

PMID35467389
PMCPMC9241680
OpenAlexW4224806117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.