Evidence map›Paper›PMID 35467325›Full record

ArticleDrug delivery and translational research2022

Amalgamation of solid dispersion and melt adsorption techniques for augmentation of oral bioavailability of novel anticoagulant rivaroxaban.

Pranav J Shah, Milan P Patel, Jigar Shah, Anroop B Nair, Sabna Kotta, Bhavin Vyas

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Pranav J ShahMaliba Pharmacy College, Uka Tarsadia University, Bardoli, Surat, 394350, India. pranav.shah@utu.ac.in.
Milan P PatelMaliba Pharmacy College, Uka Tarsadia University, Bardoli, Surat, 394350, India.
Jigar ShahDepartment of Pharmaceutics, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, India.
Anroop B NairDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Sabna KottaDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Bhavin VyasMaliba Pharmacy College, Uka Tarsadia University, Bardoli, Surat, 394350, India.
Uka Tarsadia University · INKing Abdulaziz University · SAKing Faisal University · SANirma University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the present study was to evaluate the potential of solid dispersion adsorbate (SDA) to improve the solubility and bioavailability of rivaroxaban (RXN). SDA of RXN was developed by fusion method using PEG 4000 as carrier and Neusilin as adsorbent. A 3

Indexed as

AnticoagulantsRivaroxabanAdsorptionBiological AvailabilityCaco-2 CellsCalorimetry, Differential ScanningExcipientsHumansSolubilityTabletsAnticoagulantsExcipientsRivaroxabanTabletsDissolutionFactorial designPharmacodynamicsPharmacokineticsRivaroxabanSolid dispersion adsorbate

Identifiers

PMID35467325
OpenAlexW4226060303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.