Evidence map›Paper›PMID 35467229›Full record

ArticleAIDS and behavior2022

Retention in care and viral suppression in the PMTCT continuum at a large referral facility in western Kenya.

John M Humphrey, Julia Songok, Susan Ofner, Beverly Musick, Marsha Alera, Bett Kipchumba, Megan S McHenry, James G Carlucci, Jun Park, Winfred Mwangi and 3 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. International journal of MCH and AIDS · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

John M HumphreyDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. humphrjm@iu.edu.ORCID http://orcid.org/0000-0003-3156-1065
Julia SongokDepartment of Paediatrics, Moi University College of Health Sciences, Eldoret, Kenya.
Susan OfnerDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA.
Beverly MusickDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA.
Marsha AleraAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Bett KipchumbaDepartment of Reproductive Health, Moi Teaching and Referral Hospital, Eldoret, Kenya.
Megan S McHenryDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
James G CarlucciDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Jun ParkDepartment of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
Winfred MwangiDepartment of Reproductive Health, Moi Teaching and Referral Hospital, Eldoret, Kenya.
Constantin YiannoutsosDepartment of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
Giorgos BakoyannisDepartment of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
Kara Wools-KaloustianDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

Funding

East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Leslie Anne Enane, AGGREY SEMWENDERO SEMEERE · 2006 to 2026
$57.7M
NIAID NIH HHS U01 AI069911NIH HHS U01AI069911
6 · The paper itself

Abstract

Medical records of pregnant and postpartum women living with HIV and their infants attending a large referral facility in Kenya from 2015 to 2019 were analyzed to identify characteristics associated with retention in care and viral suppression. Women were stratified based on the timing of HIV care enrollment: known HIV-positive (KHP; enrolled pre-pregnancy) and newly HIV-positive (NHP; enrolled during pregnancy). Associations with retention at 18 months postpartum and viral suppression (< 1000 copies/mL) were determined. Among 856 women (20% NHP), retention was 83% for KHPs and 53% for NHPs. Viral suppression was 88% for KHPs and 93% for NHPs, but 19% of women were missing viral load results. In a competing risk model, viral suppression increased by 18% for each additional year of age but was not associated with other factors. Overall, 1.9% of 698 infants with ≥ 1 HIV test result were HIV-positive. Tailored interventions are needed to promote retention and viral load testing, particularly for NHPs, in the PMTCT continuum.

Indexed as

Anti-HIV AgentsHIV InfectionsPregnancy Complications, InfectiousRetention in CareFemaleHumansInfantInfectious Disease Transmission, VerticalKenyaPregnancyReferral and ConsultationAnti-HIV AgentsHIVMother-to-child transmissionPregnant womenRetentionViremia

Identifiers

PMID35467229
PMCPMC9550706

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.