Evidence map›Paper›PMID 35467133›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Incidence and prevalence of Tourette syndrome and chronic tic disorders in Taiwan: a nationwide population-based study.

I-Jun Chou, Po-Cheng Hung, Jainn-Jim Lin, Meng-Ying Hsieh, Yi-Shan Wang, Cheng-Yen Kuo, Chang-Fu Kuo, Kuang-Lin Lin, Huei-Shyong Wang

Abstract read
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In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Sex Differences in Histamine Regulation of Striatal Dopamine.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

I-Jun ChouDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
Po-Cheng HungDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
Jainn-Jim LinDivision of Pediatric Critical Care and Pediatric Neurocritical Care Center, Chang Gung Children's Hospital at Linkou, Taoyuan, Taiwan.
Meng-Ying HsiehDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
Yi-Shan WangDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
Cheng-Yen KuoDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
Chang-Fu KuoDivision of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Kuang-Lin LinDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
Huei-Shyong WangDivision of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan. wanghs444@cgmh.org.tw.

Funding

chang gung memorial hospital, linkou CMRPG3J0141chang gung memorial hospital, linkou CORPG3G0411chang gung memorial hospital, linkou CORPG3G0461
6 · The paper itself

Abstract

purposeThe incidence of Tourette syndrome and chronic tic disorders has seldom been evaluated in Asia.

methodsUsing the National Taiwan Insurance Research Database, the annual standardized incidence and prevalence of Tourette syndrome (TS) and chronic tic disorders were estimated from 2007 to 2015. The pre-existing comorbidity at disease diagnosis was also evaluated.

resultsFrom 2007 to 2015, the age- and sex-standardized incidence increased from 5.34 (95% confidence interval [CI] 5.06-5.62) per 100,000 person-years to 6.87 (95% CI 6.53-7.21) per 100,000 person-years. In children and adolescents, the age- and sex-standardized incidence increased from 19.58 (95% CI 18.42-20.75) per 100,000 person-years to 31.79 (95% CI 30.09-33.49) per 100,000 person-years. In adults, the age- and sex-standardized incidence decreased from 2.01 (95% CI 1.79-2.23) per 100,000 person-years to 1.24 (95% CI 1.07-1.42) per 100,000 person-years. The incidence rate ratio (IRR) between males and females was 3.74 (95% CI 3.32-4.22). The age- and sex-standardized prevalence increased from 37.51 (95% CI 36.75-38.27) per 100,000 people in 2007 to 84.18 (95% CI 83.02-85.35) per 100,000 people in 2015. The rate risk (RR) between males and females was 3.65 (95% CI 3.53-3.78).

conclusionThe annual incidence rates of TS and chronic tic disorders increased in childhood and adolescence but decreased in adulthood from 2007 to 2015. The prevalence rates increased over the same period.

Indexed as

Tic DisordersTourette SyndromeAdolescentAdultChildFemaleHumansIncidenceMalePrevalenceTaiwanChronic tic disordersComorbidityIncidencePrevalenceTourette syndrome

Identifiers

PMID35467133

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.