Evidence map›Paper›PMID 35467123›Full record

ArticleInternational journal of colorectal disease2022

External validation of two prediction models for adequate bowel preparation in Asia: a prospective study.

Xin Yuan, Hui Gao, Cenqin Liu, Weihong Wang, Jiarong Xie, Zhixin Zhang, Lei Xu

Registry-linked trialAbstract read
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In one paragraph

Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04607161 (External Validation of Two Prediction Models for Adequate Bowel Preparation in Asia), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04607161 completednot on this map

External Validation of Two Prediction Models for Adequate Bowel Preparation in Asia: A Prospective Study

TypeobservationalSponsorNingbo No. 1 HospitalRan2020 to 2020Enrolled500ConditionsColonoscopy, Predictive Model, External ValidationArmsno intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xin YuanSchool of Medicine, Ningbo University, Zhejiang, China.
Hui GaoSchool of Medicine, Ningbo University, Zhejiang, China.
Cenqin LiuDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Weihong WangDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Jiarong XieDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Zhixin ZhangDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Lei XuDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China. xulei22@163.com.ORCID http://orcid.org/0000-0001-6017-3745

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral models for predicting adequate bowel preparation are available but have never been externally validated. The aim of this study is to compare the available models in an independent population.

methodsThis study prospectively recruited 500 consecutive patients from August to December 2020 from the Endoscopy Center of a tertiary hospital. All patients underwent the same bowel preparation regimen. The discrimination of the prediction models was quantified with the area under the receiver operating characteristic curve (AUC), and the 95% confidence interval (CI) was calculated for each AUC.

resultsFinally, 461 patients were eligible for this study. A total of 110 (23.9%) patients were deemed to show inadequate bowel preparation during colonoscopy. There were significant differences between patients with and without adequate bowel preparation in terms of current hospitalization, procedure time, comorbidities (including diabetes and constipation), American Society of Anesthesiologists Physical Status Classification System score (ASA) ≥ 3, medication usage, and abdominal/pelvic surgery. The prediction models performed as follows: the Dik ≥ 2 model, the Dik ≥ 3 model, and the Antonio > 1.225 model had AUCs of 0.660 (95% CI = 0.604-0.717), 0.691 (95% CI = 0.646-0.733), and 0.645 (95% CI = 0.615-0.704), respectively. Comparison of the two prediction models showed no significant improvement (Antonio > 1.225 vs. Dik ≥ 3, 1.801, 95% CI =  -0.004-0.096, P = 0.072).

conclusionsBoth models are potentially helpful. However, it is necessary to develop or improve a prediction model to obtain a more suitable and detailed model.

trial registrationClinicalTrials.gov, Number NCT04607161.

Indexed as

CatharticsColonoscopyConstipationHumansProspective StudiesROC CurveCatharticsBowel preparationColonoscopyExternal validationPrediction model

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.