Evidence map›Paper›PMID 35467118›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Financial toxicity of cancer care in low- and middle-income countries: a systematic review and meta-analysis.

Andrew Donkor, Vivian Della Atuwo-Ampoh, Frederick Yakanu, Eric Torgbenu, Edward Kwabena Ameyaw, Doris Kitson-Mills, Verna Vanderpuye, Kofi Adesi Kyei, Samuel Anim-Sampong, Omar Khader and 1 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  9. Financial toxicity experienced by patients with breast cancer-related lymphedema: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  12. Association between financial toxicity and frailty among older patients with cancer: a cross-sectional study using COST and G8.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrew DonkorImproving Palliative, Aged and Chronic Care Through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, New South Wales, Sydney, Australia. Andrew.Donkor@uts.edu.au.ORCID http://orcid.org/0000-0002-6073-524X
Vivian Della Atuwo-AmpohDepartment of Medical Imaging, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.
Frederick YakanuNational Centre for Radiotherapy, Korle-Bu Teaching Hospital, Accra, Ghana.
Eric TorgbenuImproving Palliative, Aged and Chronic Care Through Clinical Research and Translation (IMPACCT), Faculty of Health, University of Technology Sydney, New South Wales, Sydney, Australia.ORCID http://orcid.org/0000-0002-1065-1718
Edward Kwabena AmeyawThe Australian Centre for Public and Population Health Research (ACPPHR), Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-6617-237X
Doris Kitson-MillsDepartment of Radiography, University of Ghana, Accra, Ghana.
Verna VanderpuyeNational Centre for Radiotherapy, Korle-Bu Teaching Hospital, Accra, Ghana.ORCID http://orcid.org/0000-0003-3656-6965
Kofi Adesi KyeiDepartment of Radiography, University of Ghana, Accra, Ghana.ORCID http://orcid.org/0000-0003-3485-5368
Samuel Anim-SampongDepartment of Radiography, University of Ghana, Accra, Ghana.
Omar KhaderFaculty of Medicine, University of Jordan, Amman, Jordan.
Jamal KhaderRadiation Oncology Department, King Hussein Cancer Centre, Amman, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe costs associated with cancer diagnosis, treatment and care present enormous financial toxicity. However, evidence of financial toxicity associated with cancer in low- and middle-income countries (LMICs) is scarce.

aimTo determine the prevalence, determinants and how financial toxicity has been measured among cancer patients in LMICs.

methodsFour electronic databases were searched to identify studies of any design that reported financial toxicity among cancer patients in LMICs. Random-effects meta-analysis was used to derive the pooled prevalence of financial toxicity. Sub-group analyses were performed according to costs and determinants of financial toxicity.

resultsA total of 31 studies were included in this systematic review and meta-analysis. The pooled prevalence of objective financial toxicity was 56.96% (95% CI, 30.51, 106.32). In sub-group meta-analyses, the objective financial toxicity was higher among cancer patients with household size of more than four (1.17% [95% CI, 1.03, 1.32]; p = 0.02; I

conclusionsThis study indicates that cancer diagnosis, treatment and care impose high financial toxicity on cancer patients in LMICs. Further rigorous research on cancer-related financial toxicity is needed.

Indexed as

Developing CountriesNeoplasmsFinancial StressHumansPovertyPrevalenceCancerFinancial toxicityLow- and middle-income countriesTreatment

Identifiers

PMID35467118
PMCPMC9385791

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.