ArticleJournal of endovascular therapy : an official journal of the International Society of Endovascular Specialists2023
Computational Fluid Dynamics for the Prediction of Endograft Thrombosis in the Superficial Femoral Artery.
Article in Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- In Vivo Validation of Computational Fluid Dynamics for Determining the Pressure Gradient for Multi-segmental Femoropopliteal Disease.Cardiovascular and interventional radiology · 2026Article
- Real-Time Peripheral Revascularization Planning in Chronic Limb Threatening Ischemia Using HarVI: A Digital Twin Approach.Cardiovascular engineering and technology · 2026Article
- Computational analysis of haemodynamics and oxygen distribution in the patient-specific aorta during VA-ECMO under various clinical scenarios.Medical & biological engineering & computing · 2026Article
- Using patient-specific computational fluid dynamics to assess intraprosthetic thrombus formation risk and guide relining after endovascular aneurysm repair.JVS-vascular science · 2026Article
- Haemodynamic study of left nonthrombotic iliac vein lesions: a preliminary report.Scientific reports · 2024Article
- Validation of ultrasound velocimetry and computational fluid dynamics for flow assessment in femoral artery stenotic disease.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Lesion Eccentricity Plays a Key Role in Determining the Pressure Gradient of Serial Stenotic Lesions: Results from a Computational Hemodynamics Study.Cardiovascular and interventional radiology · 2024Article
- Beyond CFD: Emerging methodologies for predictive simulation in cardiovascular health and disease.Biophysics reviews · 2023Review
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Authors and funding
5 authors.
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Abstract
purposeContemporary diagnostic modalities, including contrast-enhanced computed tomography (CTA) and duplex ultrasound, have been insufficiently able to predict endograft thrombosis. This study introduces an implementation of image-based computational fluid dynamics (CFD), by exemplification with 4 patients treated with an endograft for occlusive disease of the superficial femoral artery (SFA). The potential of personalized CFD for predicting endograft thrombosis is investigated. MATERIALS AND
methodsFour patients treated with endografts for an occluded SFA were retrospectively included. CFD simulations, based on CTA and duplex ultrasound, were compared for patients with and without endograft thrombosis to investigate potential flow-related causes of endograft thrombosis. Time-averaged wall shear stress (TAWSS) was computed, which highlights areas of prolonged residence times of coagulation factors in the graft.
resultsCFD simulations demonstrated normal TAWSS (>0.4 Pa) in the SFA for cases 1 and 2, but low levels of TAWSS (<0.4 Pa) in cases 3 and 4, respectively. Primary patency was achieved in cases 1 and 2 for over 2 year follow-up. Cases 3 and 4 were complicated by recurrent endograft thrombosis.
conclusionThe presence of a low TAWSS was associated with recurrent endograft thrombosis in subjects with otherwise normal anatomic and ultrasound assessment and a good distal run-off.
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