Evidence map›Paper›PMID 35466766›Full record

ArticleJournal of biomaterials applications2022

In vitro and In vivo assessment of a novel organ perfusion stent for successful flow separation in donation after cardiac death.

Moataz Elsisy, Bryan Tillman, Lynn Chau, Catherine Go, Sung Kwon Cho, Youngjae Chun

Open access · greenAbstract read
In one paragraph

Article in Journal of biomaterials applications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Moataz ElsisyDepartment of Industrial Engineering, 6614University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-6275-7568
Bryan Tillman12306The Ohio State University Medical Center, Columbus, OH, USA.
Lynn ChauDepartment of Bioengineering, 6614University of Pittsburgh, Pittsburgh, PA, USA.
Catherine Go6595University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Sung Kwon Cho110071University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA, USA.
Youngjae ChunDepartment of Industrial Engineering, 6614University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-4522-7116
University of Pittsburgh · USThe Ohio State University Wexner Medical Center · USUniversity of Pittsburgh Medical Center · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
An Organ Perfusion Stent as an Alternative to Surgery in Donor Organ RecoveryR01EB022591 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHUN, YOUNG JAE, TILLMAN, BRYAN W. · 2017 to 2020
$1.3M
NCATS NIH HHS UL1 TR000005NIBIB NIH HHS R01 EB022591
6 · The paper itself

Abstract

Shortage of healthy donors' organs has appeared as one of the main challenges for organ transplantation. This study focuses on the novel endovascular device development to increase the number of available organs from cardiac death donors. The primary objective of this study is the design validation of a newly developed stent graft for the abdominal organ perfusion with cardiac blood flow isolation. In this paper, the effectiveness of the device design has been validated via the assessment of the device performance both in vitro and in vivo. The radial force of stent structure was first numerically analyzed using finite element method, then was quantified experimentally. The blood perfusion parameters were investigated to demonstrate their effect on the blood delivered to the abdominal organs, maintaining the organs healthy for donation.

Indexed as

DeathStentsAnimalsHumansPerfusionSwineTissue Donorsdonation after cardiac deathendovascular deviceexpandable polytetrafluoroethyleneNitinolOrgan perfusion stent

Identifiers

PMID35466766
PMCPMC9578539
OpenAlexW4224322885

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.