Evidence map›Paper›PMID 35466599›Full record

ArticleJournal of veterinary science2022

Effect of oral antioxidants on the progression of canine senile cataracts: a retrospective study.

Sanghyun Park, Seonmi Kang, Sukjong Yoo, Youngwoo Park, Kangmoon Seo

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Oxidative Stress in Canine Diseases: A Comprehensive Review.Antioxidants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sanghyun ParkDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0000-0002-5039-5982
Seonmi KangDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0000-0001-8017-0891
Sukjong YooYoolim Animal Eye Clinic, Seoul 06524, Korea.ORCID https://orcid.org/0000-0002-3284-6284
Youngwoo ParkDaegu Animal Medical Center, Daegu 42185, Korea.ORCID https://orcid.org/0000-0002-5161-3881
Kangmoon SeoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. kmseo@snu.ac.kr.ORCID https://orcid.org/0000-0001-6645-7116
Seoul National University · KRKim's Eye Hospital · KR

Funding

Seoul National University
6 · The paper itself

Abstract

backgroundCataracts are the leading cause of impaired vision or blindness in dogs. There are many antioxidants that can prevent cataract progression, but whether they are clinically effective in dogs has not been established.

objectivesTo analyze the delaying or preventing effect of oral antioxidants on canine senile cataracts through retrospective analysis.

methodsMedical records of dogs from January 1, 2015 to July 10, 2020 were reviewed. Dogs that were 8 yr of age or older with senile cataracts were included in this study. The dogs were divided into two treatment groups (dogs administered with Ocu-GLO supplement and dogs administered with Meni-One Eye R/C supplement) and a control group (dogs that were not administered any supplement). Dogs with incipient and immature cataracts were included in this study. Altogether, 112 dogs (156 eyes) with incipient cataracts and 60 dogs (77 eyes) with immature cataracts were included. The period of time that cataracts progressed from incipient to immature, and from immature to mature was recorded for each dog.

resultsThere was no significant delaying effect on the progression of incipient cataracts. However, both Ocu-GLO (hazard ratio = 0.265,

conclusionsAlthough there was no significant delaying effect of oral antioxidants on incipient cataract progression, antioxidants could be used to delay the progression of senile immature cataract.

Indexed as

CataractDog DiseasesAnimalsAntioxidantsDogsEyeRetrospective StudiesAntioxidantsAntioxidantcataractdogpreventionsupplement

Identifiers

PMID35466599
PMCPMC9149495
OpenAlexW4224529721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.