Evidence map›Paper›PMID 35466442›Full record

Observational studyArtificial organs2022

Incidence and risk factors of deep vein thrombosis after extracorporeal life support.

Olivier van Minnen, Walter M van den Bergh, Joep M Droogh, Lisette Koehorst, Wim K Lagrand, S Jorinde Raasveld, Annemieke Oude Lansink-Hartgring, Aart Terpstra, Jasper M Smit, Pieter R Tuinman and 1 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Assessing Venous Thrombotic Risks in Extracorporeal Membrane Oxygenation-Supported Patients: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  2. Article
  3. Serum lncRNA RAMP2-AS1 Served as a Biomarker of Deep Vein Thrombosis Occurrence and Development in Elderly.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Olivier van MinnenDepartment of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-4315-4072
Walter M van den BerghDepartment of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Joep M DrooghDepartment of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Lisette KoehorstDepartment of Radiology, Amsterdam University Medical Center (Location AMC), University of Amsterdam, Amsterdam, The Netherlands.
Wim K LagrandDepartment of Intensive Care Medicine, Amsterdam University Medical Center (Location AMC), University of Amsterdam, Amsterdam, The Netherlands.
S Jorinde RaasveldDepartment of Intensive Care Medicine, Amsterdam University Medical Center (Location AMC), University of Amsterdam, Amsterdam, The Netherlands.
Annemieke Oude Lansink-HartgringDepartment of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Aart TerpstraDepartment of Radiology, Amsterdam University Medical Center (Location AMC), University of Amsterdam, Amsterdam, The Netherlands.
Jasper M SmitDepartment of Intensive Care Medicine, Amsterdam University Medical Center (Location VUmc), Vrije Universiteit, Amsterdam, The Netherlands.
Pieter R TuinmanDepartment of Intensive Care Medicine, Amsterdam University Medical Center (Location VUmc), Vrije Universiteit, Amsterdam, The Netherlands.
Alexander P J VlaarDepartment of Intensive Care Medicine, Amsterdam University Medical Center (Location AMC), University of Amsterdam, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep vein thrombosis (DVT) after decannulation of extracorporeal life support (ECLS) is not uncommon. Moreover, the impact of anticoagulation and potential risk factors is unclear. Furthermore, it is unclear if cannula-associated DVT is more common in ECLS patients compared to critically ill patients without ECLS.

methodsAll adult patients who were successfully weaned from ECLS and were screened for DVT following decannulation were included in this observational cohort study. The incidence of post-ECLS-DVT was assessed and the cannula-associated DVT rate was compared with that of patients without ECLS after central venous catheter (CVC) removal. The correlation between the level of anticoagulation, risk factors, and post-ECLS-DVT was determined.

resultsWe included 30 ECLS patients and 53 non-ECLS patients. DVT was found in 15 patients (50%) of which 10 patients had a DVT in a cannulated vein. No correlation between the level of anticoagulation and DVT was found. V-V ECLS mode was the only independent risk factor for post-ECLS-DVT (OR 5.5; 95%CI 1.16-26.41). We found no difference between the ECLS and non-ECLS cohorts regarding cannula-associated DVT rate (33% vs. 32%).

conclusionPost-ECLS-DVT is a common finding that occurs in half of all patients supported with ECLS. The incidence of cannula-associated DVT was equal to CVC-associated DVT in critically ill patients without ECLS. V-V ECLS was an independent risk factor for post-ECLS-DVT.

Indexed as

Extracorporeal Membrane OxygenationVenous ThrombosisAdultAnticoagulantsCritical IllnessHumansIncidenceRisk FactorsAnticoagulantsanticoagulantdeep vein thrombosisextracorporeal life support

Identifiers

PMID35466442
PMCPMC9546164
OpenAlexW4224316376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.