Evidence map›Paper›PMID 35466332›Full record

ArticleJournal of materials chemistry. B2022

Phosphonate coating of commercial iron oxide nanoparticles for nanowarming cryopreserved samples.

Jacqueline L Pasek-Allen, Randall K Wilharm, Zhe Gao, Valerie C Pierre, John C Bischof

Open access · hybridAbstract read
In one paragraph

Article in Journal of materials chemistry. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jacqueline L Pasek-AllenDepartment of Biomedical Engineering, University of Minnesota, 312 Church St. SE, Minneapolis, MN 55455, USA. pasek019@umn.edu.ORCID 0000-0002-8734-2614
Randall K WilharmDepartment of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN 55455, USA. wilha013@umn.edu.ORCID 0000-0001-7930-1452
Zhe GaoMechanical Engineering, University of Minnesota, 111 Church Street Se, Minneapolis, MN 55455, USA. gaozhemm@gmail.com.ORCID 0000-0002-5417-4984
Valerie C PierreDepartment of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN 55455, USA. wilha013@umn.edu.ORCID 0000-0002-0907-8395
John C BischofDepartment of Biomedical Engineering, University of Minnesota, 312 Church St. SE, Minneapolis, MN 55455, USA. pasek019@umn.edu.ORCID 0000-0001-6726-7111
University of Minnesota · US

Funding

Organ banking for transplant—kidney cryopreservation by vitrification and novel nanowarming technologyR01DK117425 · NIDDK · UNIVERSITY OF MINNESOTA · PI JOHN C BISCHOF, Erik Brian Finger · 2018 to 2026
$4.9M
Breakthrough Tissue and Organ Preservation and Transplantation Using Scaled-Up Nanowarming TechnologyR01HL135046 · NHLBI · UNIVERSITY OF MINNESOTA · PI BISCHOF, JOHN C, FINGER, ERIK BRIAN · 2017 to 2020
$2.6M
Advancing Kidney Nanowarming through Scaleable Coating of Iron Oxide NanoparticlesF31DK124968 · NIDDK · UNIVERSITY OF MINNESOTA · PI PASEK-ALLEN, JACQUELINE L · 2020 to 2022
$94k
NHLBI NIH HHS R01 HL135046NIDDK NIH HHS F31 DK124968NIDDK NIH HHS R01 DK117425
6 · The paper itself

Abstract

New preservation technologies may allow for organ banking similar to blood and biomaterial banking approaches. Using cryoprotective agents (CPAs), aqueous solutions with organic components such as DMSO, propylene glycol, and added salts and sugars, organs can be used to vitrify and store organs at -140 °C. When needed, these organs can be rewarmed in a rapid and uniform manner if CPAs are supplemented with iron oxide nanoparticles (IONPs) in an applied radiofrequency field. Speed and uniformity of warming are both IONP concentration and CPA suspension dependent. Here we present a coating method of small molecule phosphonate linker (PLink) and biocompatible polymer (

Indexed as

OrganophosphonatesCryopreservationCryoprotective AgentsHumansLigandsMagnetic Iron Oxide NanoparticlesWaterCryoprotective AgentsLigandsOrganophosphonatesWater

Identifiers

PMID35466332
PMCPMC9116443
OpenAlexW4224766882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.