ArticleContemporary clinical dentistry
Evaluation of Platelet-Rich Fibrin Matrix as a Regenerative Material in the Surgical Management of Human Periodontal Intraosseous Defects - A Randomized Controlled Trial.
Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Platelet Rich Fibrin Matrix (PRFM) and Peripheral Blood Mesenchymal Stem Cells (PBMSCs) in the management of intraosseous defects - A randomized clinical trial.Journal of applied oral science : revista FOB · 2024Trial
- Short-Term Bone Healing in Anterior Maxillary Sockets Using L-PRF With or Without Synthetic HA/β-TCP: A Randomized Clinical Trial.Journal of functional biomaterials · 2025Article
- Treatment of an endodontic-periodontal lesion using peripheral blood mesenchymal stem cells (PBMSCs) and platelet-rich fibrin matrix (PRFM): A case report.Journal of advanced periodontology & implant dentistry · 2025Article
- Comparative evaluation of mechanical properties of leukocyte rich platelet rich fibrin, advanced-platelet rich fibrin, titanium-platelet rich fibrin, selphyl platelet rich fibrin matrix and merisis platelet rich fibrin matrix.Biomaterial investigations in dentistry · 2025Article
- Critical review of minimally invasive periodontal surgery literature, a bibliometric study.Journal of Indian Society of PeriodontologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Platelet-rich fibrin matrix (PRFM) has not been extensively studied as other platelet concentrates such as Choukron's platelet-rich fibrin (PRF). This randomized controlled trial aimed to evaluate PRFM regenerative ability in human periodontal intrabony defects. Materials and Methods: Fifteen patients (age: 30-55 years) having probing pocket depth (PPD) ≥6 mm, and radiographic evidence of bilateral vertical intrabony defects were recruited. A split-mouth design was used in each patient; one quadrant of the arch was treated with open flap debridement (OFD) alone (control group) and the other quadrant with OFD + PRFM (test group). The PRFM was prepared by dual-spin technology using a patented thixotropic separator gel. Outcome measures comprising plaque index, gingival index (GI), PPD, clinical attachment level (CAL), depth of the defect, defect fill (DF), and percentage of DF (PDF) were recorded at baseline, after 3 months and 6 months. The parameters were applicably analyzed using the Friedman test, Fisher's exact test, Results: The GI, a net reduction in CAL, and PPD of the test group were significantly better than the control group at 3 months and 6 months ( Conclusion: PRFM can be a clinically significant periodontal regenerative material in the treatment of vertical intraosseous defects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.