Evidence map›Paper›PMID 35466275›Full record

ReviewAntibodies (Basel, Switzerland)2022

Emerging Role of Antibody-Drug Conjugates and Bispecific Antibodies for the Treatment of Multiple Myeloma.

Waqqas Tai, Ahsan Wahab, Diana Franco, Zunairah Shah, Aqsa Ashraf, Qurrat-Ul-Ain Abid, Yaqub Nadeem Mohammed, Darshan Lal, Faiz Anwer

Open access · goldAbstract readReview
In one paragraph

Review in Antibodies (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 1 country.

Waqqas TaiDepartment of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY 11201, USA.ORCID 0000-0003-1862-0868
Ahsan WahabDepartment of Internal Medicine, Prattville Baptist Hospital, Prattville, AL 36066, USA.
Diana FrancoDepartment of Internal Medicine, Loyola MacNeal Hospital, Berwyn, IL 60402, USA.ORCID 0000-0001-5360-1529
Zunairah ShahDepartment of Internal Medicine, Weiss Memorial Hospital, Chicago, IL 60640, USA.
Aqsa AshrafDepartment of Internal Medicine, Northwell Health, Mather Hospital, Port Jefferson, NY 11777, USA.
Qurrat-Ul-Ain AbidDepartment of Internal Medicine, AMITA Health Saint Joseph Hospital, Chicago, IL 60657, USA.
Yaqub Nadeem MohammedDepartment of Internal Medicine, St. Joseph Mercy Oakland Hospital, Pontiac, MI 48341, USA.ORCID 0000-0003-0547-1154
Darshan LalDepartment of Internal Medicine, University of Nevada School of Medicine, Las Vegas, NV 89102, USA.ORCID 0000-0003-0443-5602
Faiz AnwerTaussig Cancer Center, Myeloma Program, Cleveland Clinic, Cleveland, OH 44106, USA.ORCID 0000-0001-6914-7439
Brooklyn Hospital Center · USCleveland Clinic · USMacNeal Hospital · USNorthwell Health · USSaint Joseph Hospital · USSaint Thomas Midtown Hospital · USTrinity Health Oakland Hospital · USUniversity of Nevada, Las Vegas · USWeiss Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is characterized by malignant proliferation of malignant plasma cells; it is the second most common hematological malignancy associated with significant morbidity. Genetic intricacy, instability, and diverse clinical presentations remain a barrier to cure. The treatment of MM is modernized with the introduction of newer therapeutics agents, i.e., target-specific monoclonal antibodies. The currently available literature lacks the benefits of newer targeted therapy being developed with an aim to reduce side effects and increase effectiveness, compared to conventional chemotherapy regimens. This article aims to review literature about the current available monoclonal antibodies, antibody-drug conjugates, and bispecific antibodies for the treatment of MM.

Indexed as

antibodyantibody drug conjugatebispecific antibodyimmunotherapymultiple myelomatargeted therapy

Identifiers

PMID35466275
PMCPMC9036234
OpenAlexW4220697716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.