Evidence map›Paper›PMID 35466238›Full record

ArticleProteomes2022

In-Depth Quantitative Proteomics Characterization of In Vitro Selected Miltefosine Resistance in

Leonardo Saboia-Vahia, Patricia Cuervo, Jacek R Wiśniewski, Geovane Dias-Lopes, Nathalia Pinho, Gabriel Padrón, Fernando de Pilla Varotti, Silvane Maria Fonseca Murta

Open access · goldAbstract read
In one paragraph

Article in Proteomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Leonardo Saboia-VahiaGrupo de Genômica Funcional de Parasitos (GFP), Instituto René Rachou, Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.
Patricia CuervoLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0002-6245-4185
Jacek R WiśniewskiBiochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Planegg, Germany.
Geovane Dias-LopesLaboratório de Biologia Molecular e Doenças Endêmicas, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0003-4448-1398
Nathalia PinhoLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0001-8900-6748
Gabriel PadrónLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Fernando de Pilla VarottiResearch Center on Biological Chemistry (NQBio), Federal University of São João Del Rei, Divinópolis 35501-296, MG, Brazil.ORCID 0000-0002-2939-7780
Silvane Maria Fonseca MurtaGrupo de Genômica Funcional de Parasitos (GFP), Instituto René Rachou, Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.
Fundação Oswaldo Cruz · BRFederal University of São João del-Rei · BRMax Planck Institute of Biochemistry · DE

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001 P.C.-Process No. 88887.374332/2019-00Coordenação de Aperfeicoamento de Pessoal de Nível Superior G.P. - VP Process No. 0344141Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro N.P.- PD/RD Process No. E-26/200.033/2021Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro P.C.-JCNE E-26/203.253/2017Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-02816-21National Council for Scientific and Technological Development L.S.-V. - PDJ Process No. 54654/2018-3National Council for Scientific and Technological Development P.C.-Universal grant No. 423300/2018-0National Council for Scientific and Technological Development PQ-P.C. Process No. 312573/2020-0National Council for Scientific and Technological Development PQ-S.M.F.M. Process No 304158/2019-4
6 · The paper itself

Abstract

Visceral leishmaniasis (VL) is a neglected disease caused by

Indexed as

ATP synthasecytochrome c oxidaseFASPfatty acid β-oxidationLeishmania infantummass spectrometrymiltefosine resistanceoxidative phosphorylationquantitative proteomics

Identifiers

PMID35466238
PMCPMC9036279
OpenAlexW4221015850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.