ReviewJournal of functional biomaterials2022
Printability and Cell Viability in Extrusion-Based Bioprinting from Experimental, Computational, and Machine Learning Views.
Review in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 173 citations in OpenAlex.
- Machine-Learning-Assisted Quantitative Printability Assessment in Extrusion-Based Bioprinting-A Systems-Engineering Proof-of-Concept.Bioengineering (Basel, Switzerland) · 2026Article
- Bio-inks with PRF Increase Human Osteosarcoma Cell Line (SaOS-2) Viability in Extrusion-Based 3D-Bioprinted Constructs.Annals of biomedical engineering · 2026Article
- Additive Manufacturing of Biomaterials: Integrated Translational Ecosystems, Process-Structure-Property Interactions and Emerging Paradigms for Next-Generation Biomedical Engineering.Journal of functional biomaterials · 2026Review
- Computational approaches in bioprinting processes.Nature reviews bioengineering · 2026Article
- PVA:ALG Hybrid Bioink for Biofabrication of 3D Neural Models.ACS omega · 2026Article
- Innovative prospects in 3D printed bio-scaffolds for osteochondral tissue engineering: A systematic review.World journal of methodology · 2026Article
- A Formal Optimization-Oriented Design Framework for Predictive Extrusion-Based 3D Bioprinting.Biomimetics (Basel, Switzerland) · 2026Article
- Unconventional bioprinting modalities for advanced tissue biofabrication.Biomaterials · 2026Review
- Advanced additive manufacturing in orthopedics: a comprehensive review of biomaterials, structural design, biological functions and clinical technology applications.RSC advances · 2026Review
- Advances in 3D Bioprinting: Materials, Processes, and Emerging Applications.Micromachines · 2026Review
- Parameter Optimisation in 3D Extrusion Printing of Polyhydroxybutyrate Using Design of Experiment Methodology.Journal of functional biomaterials · 2026Article
- 3D Printing with Tragacanth-Gum-Based Bioinks: A New Frontier in Bioprinting Materials.Gels (Basel, Switzerland) · 2026Review
- Beyond graphene: the MXene era in bioprinting.Biomedical engineering online · 2026Review
- Graphene and TiACS applied bio materials · 2026Article
- An asymptotic slender-body model for predicting print resolution in extrusion-based bioprinting.Journal of engineering mathematics · 2026Article
- Patient-specific 3D cryo(bio)printing of a glenoid labrum scaffold for fibrocartilaginous tissue engineering.Frontiers in bioengineering and biotechnology · 2026Article
- Engineering osteoporosis-related bone organoids: a mechanism-module-functional readout framework for disease modelling and biomarker translation.Frontiers in cell and developmental biology · 2026Review
- Bioinks in systems biology: integrating biomaterial design with cellular network modelling for predictive biofabrication.Frontiers in bioengineering and biotechnology · 2026Review
- Task-specific computational fluid dynamics evaluation of multi-outlet extrusion nozzles for bioprinting.Frontiers in bioengineering and biotechnology · 2026Article
- Advances in 3D bioprinting for medical application: opportunities and challenges.Biomedical engineering online · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Extrusion bioprinting is an emerging technology to apply biomaterials precisely with living cells (referred to as bioink) layer by layer to create three-dimensional (3D) functional constructs for tissue engineering. Printability and cell viability are two critical issues in the extrusion bioprinting process; printability refers to the capacity to form and maintain reproducible 3D structure and cell viability characterizes the amount or percentage of survival cells during printing. Research reveals that both printability and cell viability can be affected by various parameters associated with the construct design, bioinks, and bioprinting process. This paper briefly reviews the literature with the aim to identify the affecting parameters and highlight the methods or strategies for rigorously determining or optimizing them for improved printability and cell viability. This paper presents the review and discussion mainly from experimental, computational, and machine learning (ML) views, given their promising in this field. It is envisioned that ML will be a powerful tool to advance bioprinting for tissue engineering.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.