Evidence map›Paper›PMID 35465954›Full record

ArticleBritish journal of anaesthesia2022

Prevalence, characteristics, and longer-term outcomes of patients with persistent critical illness attributable to COVID-19 in Scotland: a national cohort study.

Michael C Blayney, Neil I Stewart, Callum T Kaye, Kathryn Puxty, Robert Chan Seem, Lorraine Donaldson, Catriona Haddow, Ros Hall, Caroline Martin, Martin Paton and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of anaesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Michael C BlayneyUsher Institute, University of Edinburgh, Edinburgh, UK; Public Health Scotland, UK; Department of Critical Care, NHS Lothian, Edinburgh, UK.
Neil I StewartDepartment of Critical Care, NHS Forth Valley, Larbert, UK.
Callum T KayeDepartment of Critical Care, NHS Grampian, Aberdeen, UK.
Kathryn PuxtyDepartment of Critical Care, NHS Greater Glasgow and Clyde, Glasgow, UK; School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Robert Chan SeemPublic Health Scotland, UK.
Lorraine DonaldsonPublic Health Scotland, UK.
Catriona HaddowPublic Health Scotland, UK.
Ros HallPublic Health Scotland, UK.
Caroline MartinPublic Health Scotland, UK.
Martin PatonPublic Health Scotland, UK.
Nazir I LoneUsher Institute, University of Edinburgh, Edinburgh, UK; Department of Critical Care, NHS Lothian, Edinburgh, UK. Electronic address: nazir.lone@ed.ac.uk.
Joanne McPeakeDepartment of Critical Care, NHS Greater Glasgow and Clyde, Glasgow, UK; School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
of the Scottish Intensive Care Society Audit Group
Public Health Scotland · GBNHS Greater Glasgow and Clyde · GBNHS Lothian · GBNHS Forth Valley · GBNHS Grampian · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with COVID-19 can require critical care for prolonged periods. Patients with persistent critical Illness can have complex recovery trajectories, but this has not been studied for patients with COVID-19. We examined the prevalence, risk factors, and long-term outcomes of critically ill patients with COVID-19 and persistent critical illness.

methodsThis was a national cohort study of all adults admitted to Scottish critical care units with COVID-19 from March 1, 2020 to September 4, 20. Persistent critical illness was defined as a critical care length of stay (LOS) of ≥10 days. Outcomes included 1-yr mortality and hospital readmission after critical care discharge. Fine and Gray competing risk analysis was used to identify factors associated with persistent critical Illness with death as a competing risk.

resultsA total of 2236 patients with COVID-19 were admitted to critical care; 1045 patients were identified as developing persistent critical Illness, comprising 46.7% of the cohort but using 80.6% of bed-days. Patients with persistent critical illness used more organ support, had longer post-critical care LOS, and longer total hospital LOS. Persistent critical illness was not significantly associated with long-term mortality or hospital readmission. Risk factors associated with increased hazard of persistent critical illness included age, illness severity, organ support on admission, and fewer comorbidities.

conclusionsAlmost half of all patients with COVID-19 admitted to critical care developed persistent critical illness, with high resource use in critical care and beyond. However, persistent critical illness was not associated with significantly worse long-term outcomes compared with patients who were critically ill for shorter periods.

Indexed as

COVID-19Critical IllnessAdultCohort StudiesHospital MortalityHumansIntensive Care UnitsLength of StayPrevalenceRetrospective StudiesCOVID-19intensive carelong-term ventilationmortalityoutcomereadmission

Identifiers

PMID35465954
PMCPMC8942655
OpenAlexW4220898426

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.